week1: drugs

Question 1

hemicholinium

Answer 1

inhibit the entrance of choline into cholinergic nerve so it blocks the Ach synthesis

Question 2

botulium toxin

Answer 2

block Action potential, hence decrease release of Ach into synaptic cleft

Question 3

vesamicro

Answer 3

block the storage of Ach in synaptic vesicle

Question 4

high dose nicotine

Answer 4

nicotine is alkaloid and is agonist for the nicotinic receptor; it causes inhibition in high dose

Question 5

atropine

Answer 5

antagonist blocking all muscarinic cholinergic receptor; hence it decreases the Ach neural conduction; an alkaloid

Question 6

curare

Answer 6

antagonist blocking Nm nicotinic receptors

Question 7

tubocurarine

Answer 7

antagonist blocking Nm nicotinic receptors; used as non-polarizing muscle relaxant

Question 8

hexamethonium

Answer 8

antagonist blocking Nn nicotinic receptor

Question 9

benthanecol

Answer 9

agonist of muscarinic receptors

Question 10

succinylcholine

Answer 10

agonist of Nm nicotinic receptors; continuous stimulus is possible; may lead to paralysis as a result; like尼古丁

Question 11

There are adrenergic and cholinergic receptors found on prejunctional membrane. Which types of them promote positive feedback?

Answer 11

Adrenergic: beta receptor
cholinergic: nicotinic receptor