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Stage 4: CSIM 2 > Week 3: Genetic cancers > Flashcards

Week 3: Genetic cancers Flashcards

1
Q

What 3 genes are associated with breast cancer

A

BRCA1
BRCA2
TP53

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2
Q

Which cancers are associated with BRCA

A
  • Breast
  • Melanoma
  • Ovarian
  • Pancreatic
  • Prostate
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3
Q

Components of Li Fraumeni syndrome

A
  1. Breast cancer (pre-menopausal)
  2. Brain tumour
  3. Adreno-cortical tumour
  4. Childhood sarcoma
  5. Leukaemia, Lymphoma
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4
Q

Gene associated with Li-Fraumeni syndrome

A

tp53

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5
Q

Gene associated with Familial Adenomatous

A

APC

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6
Q

Gene associated with Lynch syndrome

A

HNPCC

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7
Q

Are tumour suppressor genes or oncogenes more commonly implicated in cancers

A

Tumour suppressor genes

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8
Q

Most common oncogene cancer

A

MEN2

  • thyroid, PTH cancers
  • phaeochromocytoma
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Stage 4: CSIM 2 (47 decks)

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