Week 13 - Blood System Flashcards
Albumin
protein in blood, maintains the proper amount of water in blood
Antibody
Ab; specific protein (immunoglobulin) produced by lymphocytes in response to bacteria, viruses, or other antigens
Antigen
substance (usually foreign) that stimulates the production of an antibody
Anticoagulant
having the effect of retarding or inhibiting the coagulation of the blood
Basophil
leukocyte; responds to allergens; release histamine and heparin
Globulin
plasma protein; alpha, beta, and gamma
Coagulation
blood clotting
Differentiation
change in structure and function of a cell as it matures; specialization
Colony-stimulating factor
CSF; protein that stimulates growth of WBCs (granulocytes)
Electrophoresis
method of seperating serum proteins by electrical charge
Erythrocytes
RBC
Eosinophil
WBC containing granules that stain red; associated with allergic reactions
Fibrinogen
plasma protein that is converted to fibrin in the clotting process
Hemolytic anemia
reduction in red cells due to excessive destruction
Hematopoiesis
production of all types of blood cells including formation, development, and differentiation of blood cells
Hemoglobin
blood protein containing iron; carries oxygen in RBCs
Hematopoietic stem cell
cell in the bone marrow that gives rise to all types of blood cells
Fibrin
protein that forms the basis of a blood clot
Neutrophil
granulocytic leukocyte formed in bone marrow; phagocytic tissue-fighting cell; polymorphonuclear leukocyte
Pernicious anemia
lack of mature erythrocytes caused by inability to absorb vitamin B12 into the bloodstream
Hemolysis
destruction or breakdown of RBCs
Heparin
anticoagulant found in blood and tissue cells
Prothrombin
plasma protein; converted to thrombin in the clotting process
Rh factor
antigen on RBCs of Rh-positive individuals
Serum
plasma minus clotting proteins and cells
Stem cell
unspecialized cell that gives rise to mature specialized forms
Thrombin
enzyme that converts fibrinogen to fibrin during coagulation
Thrombocyte
platelet
Thrombosis
local coagulation or clotting of the blood in a part of the circulatory system
Reticulocyte
immature erythrocyte
Leukocyte
WBC
Lymphocyte
mononuclear leukocyte that produces antibodies
Bilirubin
orange yellow pigment in bile; formed by the breakdown of Hgb when RBCs are destroyed
Sickle cell anemia
hereditary disorder of abnormal Hgb producing sickle-shaped erythrocytes and hemolysis
Hypochromic
Cells have reduced color (less hgb)
Erthropoietin
EPO; hormone secreted by kidneys; stimulates RBC formation
Mononuclear
pertaining to a cell (leukocyte) with a single round nucleus
Macrophage
monocyte that migrates from the blood to tissue spaces; engulfs foreign material and debris
Megakaryocyte
large platelet precursor cell found in bone marrow
Monoblast
found in bone marrow, immature monocytes (macrophages)
Monocyte
leukocyte with one large nucleus; phagocyte cell that becomes a macrophage
Myeloblast
immature bone marrow that gives rise to granulocytes
Anisocytosis
RBCs are unequal in size
Phagocyte
type of cell within the body capable of engulfing and absorbing bacteria and other small cells and particles
Plasma
liquid portion of blood; contains water, proteins, salts, nutrients, lipids, hormones, and vitamins
Platelet
small blood fragment that collects at sites of injury to begin the clotting process
Plasmapheresis
removal of plasma from withdrawn blood by centrifuge. Collected cells are retransfused back int the donor.
Polymorphonuclear
pertaining to WBC with a multi-lobes; neutrophil
Immunoglobin
protein (globulin) with antibody activity IgG, IgA, IgM, IgE, IgD
Granulocytopenia
marked decrease in the number of granulocytes