week 1 contd Flashcards

1
Q

what is a dowager hump associated w/ and why

A

vertebral compression, osteoporosis

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2
Q

two most common fractures due to osteoporosis

A

vertebral compression and femoral neck

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3
Q

what is the prob w/ a femoral neck fracture

A

possible pulmonary emboli

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4
Q

osteoporosis is commonly tx w/ estrogen….what are the downsides

A

DVT, endometrial ca, breast ca

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5
Q

how to prevent osteoporosis

A

physical activity: especially before age 30
dietary ca and vit d
bisphosphonates (gross): slow down osteoclast activity

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6
Q

how to measure osteoporosis?

A

FRAX

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7
Q

what disease has excessive but weak bone

A

pagets

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8
Q

what kind of bone is disorganized in pagets

A

lamellar

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9
Q

how to check to see if someone has pagets

A

check for elevated alk phos (byprod of osteoblast activity)

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10
Q

what causes pagets

A

idiopathic: possibly paramyxoviridae

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11
Q

what is the most common symptom of pagets

A

usually asymptomatic, usually x ray finding-> mc bone pain

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12
Q

pagets has a __% chance of turning into which type of Ca

A

1, sarcoma

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13
Q

where is pagets typically found?

A

pelvis, sacrum, and skull

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14
Q

which is a typical issue w/ pagets

A

chalkstick fracture

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15
Q

what two diseases are characteristic of chalkstick fractures

A

pagets and osteopetrosis

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16
Q

who is most likely to get pagets

A

old men

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17
Q

how to tx pagets?

A

bisphosphonates

18
Q

what is characteristic about pagets

A

ivory vertebra

19
Q

what 3 diseases can have ivory vertebra

A

pagets, metastatic ca (prostate), and lymphoma

20
Q

hypocalcemia produces….

A

PTH inc. demineralize bone

21
Q

two types of vit d def

A

rickets: kids - more severe form
osteomalacia: adults - associated w/ hyperparathyoidism

22
Q

in hypoparathyroidism what happens to osteoclast activity

23
Q

hyperparathyoidism resorbs what bone

A

cortical and trabelcular

24
Q

what is the difference between compound and comminuted fractures?

A

compound: skin is ruptured
comminuted: fragmented bone

25
what type of fracture develops slowly overtime?
stress
26
how many weeks does it take for endochondral ossificiation
6-8 wks
27
what is nonuion in delayed fractures
there is a large callus formation
28
what can cause delayed healing
lack of immobilization
29
when does infection MC occur in fractures?
compound
30
what deficiencies delay fracture healing
ca, phospherous, and vit d
31
most common cause of avascular necrosis
vascular disruption via fracture
32
what are browns tumors associated w/
hyperparathyroidism
33
what are other causes of avascular necrosis
corticosteroids and idiopathic
34
what is bone marrow inflammation called
osteomyelitis
35
is osteomyelitis acute or chronic MC
acute
36
what is the most common mode of infection for osteomyelitis
hematogenous
37
osteomyelitis will have what kinds of symptoms
fever and throbbing pain
38
which disease will have a salt and pepper skull?
hyperparathyroidism
39
list the 3 areas of osteomyelitis
involucrum: lamellar, surrounds infected sequestrum: dead bone at site of infection draining sinus: abscess in surrounding soft tissue
40
caseous granulomas and bony destruction with severe deformation is
tuberculous osteomyelitis
41
most common symptom of a bone tumor... followed by
gradually increasing bone pain | then anemia