week 1 contd Flashcards

1
Q

what is a dowager hump associated w/ and why

A

vertebral compression, osteoporosis

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2
Q

two most common fractures due to osteoporosis

A

vertebral compression and femoral neck

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3
Q

what is the prob w/ a femoral neck fracture

A

possible pulmonary emboli

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4
Q

osteoporosis is commonly tx w/ estrogen….what are the downsides

A

DVT, endometrial ca, breast ca

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5
Q

how to prevent osteoporosis

A

physical activity: especially before age 30
dietary ca and vit d
bisphosphonates (gross): slow down osteoclast activity

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6
Q

how to measure osteoporosis?

A

FRAX

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7
Q

what disease has excessive but weak bone

A

pagets

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8
Q

what kind of bone is disorganized in pagets

A

lamellar

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9
Q

how to check to see if someone has pagets

A

check for elevated alk phos (byprod of osteoblast activity)

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10
Q

what causes pagets

A

idiopathic: possibly paramyxoviridae

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11
Q

what is the most common symptom of pagets

A

usually asymptomatic, usually x ray finding-> mc bone pain

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12
Q

pagets has a __% chance of turning into which type of Ca

A

1, sarcoma

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13
Q

where is pagets typically found?

A

pelvis, sacrum, and skull

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14
Q

which is a typical issue w/ pagets

A

chalkstick fracture

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15
Q

what two diseases are characteristic of chalkstick fractures

A

pagets and osteopetrosis

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16
Q

who is most likely to get pagets

A

old men

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17
Q

how to tx pagets?

A

bisphosphonates

18
Q

what is characteristic about pagets

A

ivory vertebra

19
Q

what 3 diseases can have ivory vertebra

A

pagets, metastatic ca (prostate), and lymphoma

20
Q

hypocalcemia produces….

A

PTH inc. demineralize bone

21
Q

two types of vit d def

A

rickets: kids - more severe form
osteomalacia: adults - associated w/ hyperparathyoidism

22
Q

in hypoparathyroidism what happens to osteoclast activity

A

increases

23
Q

hyperparathyoidism resorbs what bone

A

cortical and trabelcular

24
Q

what is the difference between compound and comminuted fractures?

A

compound: skin is ruptured
comminuted: fragmented bone

25
Q

what type of fracture develops slowly overtime?

A

stress

26
Q

how many weeks does it take for endochondral ossificiation

A

6-8 wks

27
Q

what is nonuion in delayed fractures

A

there is a large callus formation

28
Q

what can cause delayed healing

A

lack of immobilization

29
Q

when does infection MC occur in fractures?

A

compound

30
Q

what deficiencies delay fracture healing

A

ca, phospherous, and vit d

31
Q

most common cause of avascular necrosis

A

vascular disruption via fracture

32
Q

what are browns tumors associated w/

A

hyperparathyroidism

33
Q

what are other causes of avascular necrosis

A

corticosteroids and idiopathic

34
Q

what is bone marrow inflammation called

A

osteomyelitis

35
Q

is osteomyelitis acute or chronic MC

A

acute

36
Q

what is the most common mode of infection for osteomyelitis

A

hematogenous

37
Q

osteomyelitis will have what kinds of symptoms

A

fever and throbbing pain

38
Q

which disease will have a salt and pepper skull?

A

hyperparathyroidism

39
Q

list the 3 areas of osteomyelitis

A

involucrum: lamellar, surrounds infected
sequestrum: dead bone at site of infection
draining sinus: abscess in surrounding soft tissue

40
Q

caseous granulomas and bony destruction with severe deformation is

A

tuberculous osteomyelitis

41
Q

most common symptom of a bone tumor… followed by

A

gradually increasing bone pain

then anemia