miscellaneous bone tumors Flashcards
what is difference between fibrous cortical defect and nonossifying fibroma
size <5= FCD
NOF= 5-6 cm
what is the tx of FCD and NOF
usually none: differentiate into cortical bone by adolescence, biopsy is not usually required
What are the categories of fibrous dysplasia from spontaneous
- monostatic
- polyostotic: multiple bone involvement
- polyostotic and cafe au lait spots and endocrinopathy
what is the disease of polystatic and cafe au lait spots
McCune Albright syndrome
Which is the most common type of fibrous dysplasia
monostatic: 70%
describe polystotic fibrous dysplasia
severe deformation usually craniofacial (50%)
when is McCune- Albright Syndrome MC
early puberty
which has “onion skinning” of periosteum
ewing sarcoma
which tumors are not true neoplasms
fibrous cortical defect and nonossification fibroma
which has neoplastic mononuclear cells
giant cell tumor of bone (GCT)
what happens in GCT
erode cortex, large, lytic
is there pain with GCT
yes, arthritis like, eccentric
what percent of GCT metastasize and where
2%, and lungs
where is 2* metastasis to bone MC
axial skeleton, proximal femur/humerus
red marrow
osteoarthritis is degeneration of
articular cartilage
which is 1* and 2*, and to who?
insidious, no trauma
injury
1* adults
2* kids
MC areas of osteoarthritis
spine, dip joints, 1st mcp, 1st tmt joint
females usually get osteoarthritis….
males
knees and hands
hips
softening and degragation associated with osteoarthritis
chondromalacia
sclerosis of bone associated with osteoarthritis
eburnation
which tumor has a “soap bubble appearance”
GCT: giant ell tumor
when does inflammation develop in relation to osteoarthritis
2*
what are subchondral cysts
when synovial fluid flows in due to subchondral fractures
which antibodies are associated with RA
anti-ccp
