neuromuscular jxn disorders Flashcards
1
Q
explain myasthenia gravis
A
degrade post-synaptic Ach receptor
2
Q
where is the lesion in MG
A
thymus: hyperplasia
3
Q
symptom of MG
A
extraoccular weakness
4
Q
main population of MG
A
females 20-30
5
Q
tx of mg
A
tensilon test: inhibit anti-Ach receptor bodies
also: worsens w/ E- stimulation
6
Q
describe lambert-eaton syndrom
A
autoantibodies inhibit pre-synaptic ca++ channels
7
Q
where is weakness in lambert eaton
A
girdles
8
Q
what is paraneoplastic w/ lambert eaton
A
small cell lung ca
9
Q
there are congenital myasthenic syndromes that alter neuromuscular jxn proteins T or F
A
t
10
Q
which infection inc Ach
A
clostridium tetani
11
Q
what kind of paralysis does botulism has
A
descending
12
Q
which infection dec. Ach
A
botulism
