Wbc Flashcards
Neutrophilia is what
Too many neutrophils
What is nuetrophilia caused by
Infection particularly bacterial infection
Inflammation
Infarction
Pregnancy
Exercise rapid shift of neutrophils from marginated pool to circulating pool
Corticosteroids
Neutrophillia toxic change
Toxic granulation
Heavy course granulation of neutrophils
Can b feature of pregnancy
Nuetrophillia left shift
Left shift means increase in non segmented neutrophils or neutrophils precursors in blood
CML what happens
Increase in all granulocytes and their precursors in blood and bone marrow
Translocation of chromosome 9 n 22
Forms Philadelphia chromosome
Bcr abl 1 gene encodes a protein with uncontrolled tyrosine kinase activity
Many divisions
CML features
Large spleen
How can cml be stopped
Inhibited by specific tyrosine kinase inhibitor
Nuteropenia
Too few neutrophils
Neutropenia causes
Chemo radiotherapy
Auto immune
Bacterial infections viral
Drugs
Hypersegmented neutrophils
Increase in avrg number of neutrophils lobes
Hypersegmented neutrophils cause
Lack of b12
Folic scid
Megaloblastic anaemia
Eosinophilia
Too many eosinophils
Eonisophil cause
Allergy
Parasitic infection
Can occur in Leukemia
Basophils
Too many basophils
Monocytosis cause
Too many monocytes
Infection or chronic inflammation