w7 integument Flashcards

1
Q

epidermis epithelium shape

A

stratified squamous keratinized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the primary cell type in epidermis

A

keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are langerhans

A

antigen-presenting cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are merkel cells

A

associated w sensory nerve fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

stratum basale what layer and what shape of cells and how many layers

A

basal layer - single layer of cuboidal to columnar basophilic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

in basal layer, basal cells attach to basal lamina by what and to neighboring cells by what

A

hemidesmosomes
desmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the thickest layer of the epidermis

A

stratum spinosum (spinous or pricle layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

stratum spinosum what shape cell and how are the nucleus

A

polyhedral cells w central nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

in stratum spinosum, cytoplasm actively synthesizes what in form of tonofibrils which attach to desmosomes

A

keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

stratum granulosum is what layer and how many layers and what shape cell

A

3-5 layers for flattened cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what layer has cytoplasm that contains keratohyalin granules that contain filaggrin and other proteins involved in keratinization

A

stratum granuolusm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what layer is strictly seen on thick skin

A

stratum lucidum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

stratum lucidum structure and cells packed w what

A

cells packed w keratin filaments

translucent layer, formed of flattened eosinophilic cells
nuclei and organelles have been lost

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

stratum corneum structure, and what are the cells called

A

cells called squames
15-20 layers thick, flattened, non-nucleated keratinized cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what layer has the cytoplasm filled w birefringent filamentous keratins and cells that contain only amorphous proteins

A

stratum corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

eumelanin
pheomelanin

A

brownish or blackish pigment
pigment found in red hair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

melanocytes are derived from what and do not form desmosomes w basal cells

A

neural crest cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

tyrosinase converts what

A

tyrosine to DOPA to melanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

melanin is stored in granules called what

A

melanosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

langerhans cells (dendritic cells) act as what presenting cells an most evident in what stratum, and what do they do

A

antigen-presenting cells
most evident in stratum spinosum
process and present antigens to T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what do merkel cells do and where are they located

A

located in the stratum basale of epidermis, and also at base of hair follicles

partially surrounded by terminal discs of sensory nerve fibers

contain dense-core neurosecretory granules
mechanoreceptors

22
Q

what does dermis do and separated from epidermis by what membrane which includes what 2 layers

A

connective tissue that supports the epidermis

separated from epidermis by basement membrane which includes (basal lamina and reticular lamina)

23
Q

dermis layers and composed of what

A

papillary layer - type VII collagen, loose connective tissue, contains dermal papillae

reticular layer - thicker, less cellular, more fibrous, contains type 1 collagen an elastic fibers

24
Q

what layer are hair follicles and glands located

A

reticular layer of dermis

25
reticular layer of dermis contains an extensive nerve plexus made up of what type of fibers
sensory and sympathetic fibers (no parasympathetic)
26
hypodermis composed of what type of connective tissue and often contains what kind of cells and is vascular or avascular
loose connective tissue binds skin to underlying organs or tissues equivalent to superficial fascia in gross anatomy often contains adipose cells contains extensive vascular network
27
is the epidermis vascular or avascular
avascular - no direct blood supply
28
subpapillary plexus vs cutaneous plexus in blood vessels
subpapillary plexus - at interface of papillary and reticular layers of the dermis (capillary loops extend upward into the dermal papillae from this plexus) cutaneous plexus - between hypodermis an reticular dermis
29
lymphatic plexuses accompany what
blood plexuses
30
arteriovenous anastomoses help w what
thermoregulation (shunt blood away from the papillary dermis to prevent heat loss when the skin is exposed to cold temp) (can increase blood flow to papillary dermis to get rid of excess heat)
31
tactile discs accompany what cells and function encapsulated or non-encapsulate
merkel's cells act as light touch and mechanoreceptors non-encapsulated
32
free nerve endings function and terminate where encapsulated or non-encapsulate
terminate in both dermis and epidermis respond to pain, temperature, itching and light touch non encapsulated
33
root hair plexuses location and function
surround the base of hair follicles detect movements of hairs
34
root hair plexuses location and function encapsulated or non-encapsulate
surround the base of hair follicles detect movements of hairs non-encapsulated
35
meissner corpuscles function location is it encapsulated or on noncapsulated
function -detect light touch location - located primarily in dermal papillae, esp in fingertips, palsm, an soles encapsulated
36
Pacinian corpuscles function and what does it surround is it encapsulated or non encapuslated
detect coarse touch, pressure or sustained touch, vibrations capsule surrounds unmyelinated axon
37
ruffini's corpuscles detects what and where is it encapsulated or noncapsulated
detect stretch and torque formed a simple capsule enclosing fluid and terminal arborizations of a sensory neuron encapsulated
38
krause end bulb what kind of receptors is it encapsulated or noncapsulated
thermoreceptors, mechanoreceptors
39
sebaceous gland located throughout the skin accept where
palms and soles
40
in eccrine sweat glands, clear cells produce what and contain what dark cells are what and produce what
clear cells produce sweat (contain abundant mitochondria and microvilli) dark cells are mucoid (produce glycoprotein involved w immune response)
41
what do myoepithelial cells in eccrine sweat glands
contract to help discharge secretion
42
apocrine sweat glands function apocrine or merocrine
merocrine
43
eccrine vs apocrine sweat glands
Eccrine sweat glands occur over most of the body and open directly onto the skin's surface. Apocrine glands open into the hair follicle
44
terminal vs vellus hair
terminal - long coarse hairs such as scalp and beard vellus - very fine such as forehead
45
hair grow cycle anagen, catagen, telogen
anagen - period of hair growth catagen - period of follicle regression telogen - period of inactivity
46
facial and pubic hair growth controlled by what
androgens
47
hair follicle parts (3)
bulb, dermal papilla
48
arrector pili muscle how does it work and what does it cause
when muscle contracts, hair becomes erect causes goose bumps small smooth muscle which connects the hair shaft to the papillary dermis
49
hair color caused by melanin, produced by what where
melanocytes in the bulb
50
eponychium
staratum corneum of skin fold forms cuticle
51
distal free end of nail plate called what
hyponychium