w7 bone Flashcards

1
Q

what is the shaft of long bones

A

diaphysis

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2
Q

what is the articular end of long bones

A

epiphysis

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3
Q

what is the growth region between diaphysis and epiphysis of long bones

A

epiphyseal plate/disc

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4
Q

what is the transitional area between diaphysis and epiphyseal plate o flong bones

A

metaphysis

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5
Q

bone made of what type collagen fibers

A

type 1 collagen fibers

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6
Q

how much of the bone is inorganic component and what is a main component

A

about 65% of dry weight of bone

hydroxyapatite

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7
Q

where are osteogenic (osteoprogenitor) cells located

A

found in the deepest layer of periosteum, adjacent to the endosteum

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8
Q

osteogenic cells derived from what

A

mesenchyme

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9
Q

osteogenic cells undergo cell division to give rise to what

A

osteoblast

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10
Q

osteoblast found where

A

on periosteal and endosteal surfaces of bone

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11
Q

how to osteoblast communicate

A

by gap junctions

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12
Q

role of osteoblasts

A

SECRETE THE BONE MATRIX, SIGNALING

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13
Q

when does an osteoblast become an osteocyte

A

when an osteoblast surrounds itself w matrix

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14
Q

where are osteocytes located

A

in LACUNA

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15
Q

osteocytes processes of adjacent cells connected by what

A

gap junctions

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16
Q

role of osteocytes

A

maintain BONE MATRIX, MECHANOTRANSDUCTION

17
Q

how do osteoclasts attach to bone, and what does that surround

A

attach to bone by SEALING ZONE,
which surrounds a RUFFLED BORDER

18
Q

role of osteoclasts

A

BONE RESORPTION, SIGNALING

19
Q

compact bone tissue located where and laid down where

A

located in peripherla part of bone and laid down in OSTEONS (harversian system)

20
Q

lamellae 3 types and location

A

concentric (haversian) - form the osteon itself
interstitial - between osteons
circumferential - around outside and inside of bone

21
Q

what does the periosteum do

A

nourish bone tissue, provide supply of new osteoblasts for appositional bone growth or repair

22
Q

what does the endosteum do

A

covers internal surface of bone (trabeculae, walls of marrow cavity)

23
Q

spongy bone (cancellous or trabecular bone) formed from what

A

interconnecting trabecular (tissue elemnt in the form of a small beam, strut, or rod)

24
Q

where is the spongy bone located

A

marrow spaces between trabeculae

25
Q

periosteum of the skull is called what

A

pericranium

26
Q

bones of the skull have 2 external bony tables separated by spongy bone called what

A

diploic bone

27
Q

what is marrow

A

cellular material occuyping spaces inside bone

28
Q

what does red marrow consist of

A

developing blood cells
contains reticular cells and reticular fibers
has abudnat sinusoids

29
Q

what does yellow marrow consist of

A

adipose tissue found within medullary cavity

30
Q

which marrow type replaces the other as people age

A

yellow replaces red marrow

31
Q

what does parathyroid hormone do

A

stimulate bone resorption, thus elevating blood calcium levels

32
Q

what does calcitonin do and what gland is it secreted by

A

inhibits osteoclast activity, and promotes urinary excretion of calcium and phosphate

secreted by thyroid gland

33
Q

what does sex steroids do

A

promote bone growth during adolescence and prevent bone loss in adulthood