w7 bone Flashcards

1
Q

what is the shaft of long bones

A

diaphysis

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2
Q

what is the articular end of long bones

A

epiphysis

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3
Q

what is the growth region between diaphysis and epiphysis of long bones

A

epiphyseal plate/disc

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4
Q

what is the transitional area between diaphysis and epiphyseal plate o flong bones

A

metaphysis

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5
Q

bone made of what type collagen fibers

A

type 1 collagen fibers

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6
Q

how much of the bone is inorganic component and what is a main component

A

about 65% of dry weight of bone

hydroxyapatite

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7
Q

where are osteogenic (osteoprogenitor) cells located

A

found in the deepest layer of periosteum, adjacent to the endosteum

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8
Q

osteogenic cells derived from what

A

mesenchyme

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9
Q

osteogenic cells undergo cell division to give rise to what

A

osteoblast

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10
Q

osteoblast found where

A

on periosteal and endosteal surfaces of bone

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11
Q

how to osteoblast communicate

A

by gap junctions

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12
Q

role of osteoblasts

A

SECRETE THE BONE MATRIX, SIGNALING

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13
Q

when does an osteoblast become an osteocyte

A

when an osteoblast surrounds itself w matrix

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14
Q

where are osteocytes located

A

in LACUNA

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15
Q

osteocytes processes of adjacent cells connected by what

A

gap junctions

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16
Q

role of osteocytes

A

maintain BONE MATRIX, MECHANOTRANSDUCTION

17
Q

how do osteoclasts attach to bone, and what does that surround

A

attach to bone by SEALING ZONE,
which surrounds a RUFFLED BORDER

18
Q

role of osteoclasts

A

BONE RESORPTION, SIGNALING

19
Q

compact bone tissue located where and laid down where

A

located in peripherla part of bone and laid down in OSTEONS (harversian system)

20
Q

lamellae 3 types and location

A

concentric (haversian) - form the osteon itself
interstitial - between osteons
circumferential - around outside and inside of bone

21
Q

what does the periosteum do

A

nourish bone tissue, provide supply of new osteoblasts for appositional bone growth or repair

22
Q

what does the endosteum do

A

covers internal surface of bone (trabeculae, walls of marrow cavity)

23
Q

spongy bone (cancellous or trabecular bone) formed from what

A

interconnecting trabecular (tissue elemnt in the form of a small beam, strut, or rod)

24
Q

where is the spongy bone located

A

marrow spaces between trabeculae

25
periosteum of the skull is called what
pericranium
26
bones of the skull have 2 external bony tables separated by spongy bone called what
diploic bone
27
what is marrow
cellular material occuyping spaces inside bone
28
what does red marrow consist of
developing blood cells contains reticular cells and reticular fibers has abudnat sinusoids
29
what does yellow marrow consist of
adipose tissue found within medullary cavity
30
which marrow type replaces the other as people age
yellow replaces red marrow
31
what does parathyroid hormone do
stimulate bone resorption, thus elevating blood calcium levels
32
what does calcitonin do and what gland is it secreted by
inhibits osteoclast activity, and promotes urinary excretion of calcium and phosphate secreted by thyroid gland
33
what does sex steroids do
promote bone growth during adolescence and prevent bone loss in adulthood