cell 1: cytoplasm Flashcards

1
Q

all cells originate from a

A

zygote, which undergoes repeated cell divisions

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2
Q

cells that have not differentiated and havent reached their mature form

A

stem cells

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3
Q

what does the cytoplasm consist of

A

cytosol
organelles
cytoskeleton
inclusions
everything except the nucleus

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4
Q

cell is separated from the external environment by what

A

the plasma membrane (plasmalemma)

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5
Q

what does the plasma membrane consist of

A

2 layers of phospholipid molecules
cholesterol

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6
Q

integral vs peripheral protein on the plasma membrane

A

integral - embedded in the phospholipid bilayer
peripheral - attached to the inner or outer surface

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7
Q

glycocalyx function and location and composition

A

-involved in cell recognition and attachment to other cells or extracellular matrix
-covers outer surface of the membrane
-made of glycolipids, glycoporteins - have carbohydrate molecules attached

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8
Q

water passes through what

A

aquaporins

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9
Q

endocytosis

A

the process of bringing materials into the cell

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10
Q

phagocytosis

A

-engulfing of bacterial, protozoa, dead cells or extracellular debris
-these materials become surrounded by membrane and form a phagosome (phagocytic vesicle)

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11
Q

what are 2 phagocytic cells

A

macrophages
neutrophils

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12
Q

pinocytosis

A

engulfing of extracellular fluid and dissolved materials

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13
Q

transcytosis

A

movement of pinocytic vesicles across a cell

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14
Q

clathrin

A

one of the main coating proteins

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15
Q

receptor-mediated endocytosis

A

after ligand binding to surface receptors, the receptor-ligand complex is engulfed in coated pits, eventually forming coated vesicles

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16
Q

a transient increase in what allows exocytosis to occur

A

increase in cytosolic Ca2+

17
Q

cells receive signals called

A

target cells

18
Q

endocrine signaling includes what

19
Q

how are hormones carried out

A

in the blood

20
Q

how does paracrine signaling work

A

chemical signals act on local cells

21
Q

how does autocrine signaling work

A

signals bind to receptors on the same

22
Q

how does synaptic signaling work

A

neurotransmitter molecules are released at special cell junctions, called synapses
chemical signals are converted to electrical signals

23
Q

how does hydrophilic signaling work

A

-typically polypeptide hormones or neurotransmitters
-activate receptors on cell surfaces
-channel-linked, enzymatic, G-protein-coupled
-signal transduced by second messenger, starting a cascade of biochemical events

24
Q

how does hydrophobic signaling work

A

-bind to carrier proteins, which transport signaling molecules in the bloodstream
-signaling molecules are released, penetrate the plasma membrane, and bind to intracellular receptors
-receptor-hormone complex moves into the nucleus, binds to DNA, prompting gene transcription

25
what is synthesized in ribosome nucleolus and why does it stain intensely basophilic
rTNA syntehsized bc of phosphates
26
what does rough ER do and stains basophilic bc of what
segregation of proteins not destined for cytosol, assembly of multichain proteins, posttranslational changes of newly formed peptides bc of ribosomes
27
does smooth ER have ribosomes and what is its function
-synthesis of membrane phospholipids -steroid synthesis -degradation of toxins and drugs -sequestering Ca2+ ions (in SARCOPLASMIC RETICULUM of muscle)
28
golgi apparatus roles
-modifies proteins (glycosylation, sulfation, phosphorylation, proteolysis) -packages, concentrates and stores secretory products in VESICLES
29
ZYGOGEN GRANULES contain what
digestive enzymes
30
secretory vesicles/granulues originate from where and function
originate from golgi apparatus store secretion products until release is stimulated by metabolic, hormonal, or neural message
31
lysosome contains what enzymes
hydrolytic enzymes in acid pH "-eases"
32
lysosomes are abundant in what cells
phagocytic cells
33
lysosomes formed where and proteins labeled w what
formed by golgi apparatus proteins labled with MANNOSE-6-PHOSPHATE (M6P)
34
w lysosomes, what remains after digestion and contains undigested materials
RESIDUAL BODY
35
ETC enzymes embedded where and matrix enzymes involved w what
ETC enzymes embedded in inner membrane matrix enzymes involved w citric acid cycle
36
proteasome roles
(cylindrically shaped cytoplasmic protein complexes) -recognize ubiquitin-labled proteins -degrade denatured or nonfunctional proteins -remove proteins not needed by the cell (thus, limit time of protein activity)
37
peroxisome function and how
-utilize oxygen to make hydrogen peroxide -catalase in peroxisome breaks down H2O2
38
what are inclusions
nonmotile, non-metabolic -are not organelles -ex: fat droplets, glycogen granules, lipofuscin granules