W7 - Excretion Flashcards

1
Q

What are the 3 forms excretion can be in

A

fluids
solid
gasses

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2
Q

what are some example of fluid excretion

A
urine
bile
sweat
tears
breast milk
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3
Q

what are some examples of solid excretion

A

faces , hair

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4
Q

what are some examples of gas excretion

A

expired air

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5
Q

What are the 3 components of renal excretion

A

glomerular
reabsorption
tubular secretion

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6
Q

how do we calculate total renal excretion

A

Glomerular filtrate + tubular secretion - reabsorption

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7
Q

what size molecules are allowed to pass through the glomerulus

A

20kDa molecule and below

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8
Q

Where are the renal tubule secretory transporters

A

both basolateral and apical membrane

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9
Q

what do the secretory transporters do

A

transport acidic organic transporters or basic compounds

It can result rapid decrease in plasma concentration of unbound drug causing a rapid dissociation of any drugs bound to protiens in the plasma

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10
Q

What factors affect excretion

A

blood flow

kinetics

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