W1 - W2 Lymphatic organs lab-manual Flashcards
What is this slide about?
Thymus (lymphatics) - HE - human
Name of this cell. 2 Functions?
Eosinophill in medulla
Functions:
- may participate directly in the selection of T cells
- ability of eosinophils to present antigen to T cells
Thymus (lymphatics) - HE - human
Identify
43c. Thymus (lymphatic) - newborn human - pancytoleratin immunocytochemistry - HE
Identify
cytokeratin negative zones
43c. Thymus (lymphatic) - newborn human - pancytoleratin immunocytochemistry - HE
43a. Thymus (lymphatics) - HE - human
CORTEX - epithelial cells surround a capillary
43a. Thymus (lymphatics) - HE - human
Name of this area and structures
MEDULLA - macrophages
43a. Thymus (lymphatics) - HE - human
Name of this area and structures
MEDULLA - Hassel’s body
49)Thymus (H-E)
Identify
1) cortex.
2) medulla.
3) Hassalls corpuscles.
4) CT septum.
5) T-lymphocytes (mature).
5*) T-lymphocyte (immature).
49)Thymus (H-E) - medulla
5) T-lymphocytes (mature).
6) reticular cells.
49)Thymus (H-E) - CORTEX
5) T-lymphocytes (mature).
6) reticular cells.
49)Thymus (H-E)
Identify
7) Lobules
Hassles corpuscles (3) made of ____
degenerated epitheloid reticular cells)
49)Thymus (H-E)
Identify
5)T-lymphocytes (mature).
M)Macrophage.
49)Thymus (H-E)
Identify E
E)Epithelial cell part of Hassalls corpuscles (nuclei type 6).
Thymus - Netter
→ identify
- Capsule
- Hassal’s corpuscles
- Lymphocytes
- Capillaries
- Epithelial reticular cell
The precursors of T-lymphocytes divide in ____ in thymus
the cortex (the majority will die and these cells are phagocyted by macrophages).
The precursors of T-lymphocytes divide in the cortex (the majority will die and these cells are phagocyted by macrophages).
→ Surviving T-lymphocytes are able to ___ (function?)
recognize the MHC of the body.
Surviving T-lymphocytes are able to recognize the MHC of the body.
→ later they will be able to differentiate further and ___ (function)
respond exogenous antigenic stimuli with specific reactions.
The precursors of T-lymphocytes divide in the cortex (the majority will die and these cells are phagocyted by macrophages).
→ Mature T-lymphocytes enters ____
THYMUS
The differentiation of the lymphocytes in the cortex happens behind ____
the blood thymus-barrier
THYMUS
The differentiation of the lymphocytes in the cortex happens behind the blood thymus-barrier
→ this barrier is made by ___ (4 things)
- the endothelial cells
- the basal lamina of the capillary
- the perivascular C.T
- the basal lamina of the reticular cells!!.
mature T-lymphocytes leave thymus through ___
vessels (4) situated at the cortex-medulla border.
49)Thymus (H-E)
After puberty thymus (especially the cortex) degenerates and become ___
adipose thymus.
*all the lymph organs except ____ contain lymphatic follicle.
thymus
On the route surface capsule or epithelium can be found:
→ capsule is present in ___ and ___
lymph node and spleen.
the lymphoepithelial organs have epithelial covering
→ These organs are __
tonsils,Peyer’s patchesandvermiform appendix.
Tonsils are covered by oral (stratified squamous non - keratinized) epithelium
→ these tonsils are ___
lingual and palatine tonsils.
Which tonsils are covered by respiratory (pseudostratified columnar ciliated epithelium)?
Other (pharyngeal and tubarian)tonsils
___ tonsil specimens contains also the cartilage of the auditory tube.
Tubarian
intestinal lymphoepithelial organs are covered by ____ antimesenterial side of the lumen
simple columnar epithelium
appendix contains ____ in the submucosa all along the organ.
aggregation lymphatic follicle
What is this slide about?
47) palatine tonsil (H-E)
47)palatine tonsil (H-E).
→ the organ is separated from the surrounding tissue components by ___
a CT capsule (5) made by collagen fibers and fibrocytes.
47)palatine tonsil (H-E).
→ the free luminal surface is lined by ___
stratified squamous non keratinized epithelium (1) (covering the walls of the crypts as well).
47)palatine tonsil (H-E).
→ under the epithelium ___ are visible.
the secondary lymphatic follicles (2) with germinal centers
