Endocrine system slides (90, 86, 87) Flashcards
Figure 86/A-B. Pituitary gland
A: : Parts of the pituitary gland and thehypothalamo-hypophyseal tracts
-> Identify 1 -> 5
- posterior lobe, neurohypophysis
- pars intermedia
- anterior lobe, adenohypophysis
- pars distalis
- pars tuberalis
Figure 86/A-B. Pituitary gland
A: : Parts of the pituitary gland and thehypothalamo-hypophyseal tracts
-> Identify 11 -> 15
- tuberoinfundibular tract
- median eminence
- infundibular recess
- hypothalamo-hypophyseal tract
- infundibulum
Figure 86/A-B. Pituitary gland
A: : Parts of the pituitary gland and thehypothalamo-hypophyseal tracts
-> Identify 6 -> 10
- optic chiasm
- supraoptic nucleus
- paraventricular nucleus
- tuberal nuclei
- tuber cinereum
Figure 86/A-B. Pituitary gland
B: The portal circulation
-> Identify
1/ posterior lobe, neurohypophysis
2/ pars intermedia
4/ pars distalis
5/ pars tuberalis
11/ tuberoinfundibular tract
12/ median eminence
14/ hypothalamo-hypophyseal tract
16/ inferior hypophyseal artery
17/ cavernous sinus
18/ portal veins
19/ superior hypophyseal artery
What are the 2 parts of the hypophysis?
1) Adenohypophysis (anterior pituitary) (3)
2) Neurohypophysis (posterior pituitary) (1)
What are the 2 parts of the hypophysis?
1) Adenohypophysis (anterior pituitary) (3)
2) Neurohypophysis (posterior pituitary) (1)
Adenohypophysis
-> The pars intermedia (2) is situated between ___ and ____
the pars distalis and the neurohypophysis
Adenohypophysis (anterior pituitary) (3) Is composed of the pars distalis (4), the pars tuberalis (5) and the pars intermedia (2)
=> All these develop from ____
Rathke’s pouch (placod ectoderm diverticulum).
In Adenohypophysis (anterior pituitary), which part has the largest proportion?
Pars distalis
What is the embryological origin of Neurohypophysis?
Derived from the floor of the diencephalon.
Figure 86/C. Pituitary gland
-> identify 1 -> 4
- posterior lobe, neurohypophysis
- pars intermedia
- anterior lobe, adenohypophysis
- pars distalis
Figure 86/C. Pituitary gland
-> identify 20 -> 27
- chromophobe cell
- connective tissue
- acidophil cell
- basophil cell
- sinusoid capillary
- cyst of Rathke
- basophil cells of the
pars intermedia b - pituicytes
Figure 86/C. Pituitary gland
Adenohypophysis, pars distalis (3, 4): endocrine epithelial cells form ____
anastomosing cords or clumps which are surrounded by a rich network of sinusoid capillaries (24).
Figure 86/C. Pituitary gland
Adenohypophysis, pars distalis (3, 4): endocrine epithelial cells form anastomosing cords or clumps which are surrounded by a rich network of sinusoid capillaries (24).
=> A fine meshwork of ____ supports the parenchyma.
connective tissue fibres (21)
Figure 86/C. Pituitary gland
-> The secretory cells of the parenchyma have been classified according to their staining characteristics.
-> What are the 2 classifications?
- chromophils (which are stained well) and
- chromophobes (20) (which are not stained).
Figure 86/C. Pituitary gland
-> Adenohypophysis, pars distalis (3, 4)
-> The chromophils are subdivided into two groups which are ___
- acidophils (22) (80%) and
- basophils (23) (20% of chromophils)
(due to their affinity for acidic and basic dyes.)
Figure 86/C. Pituitary gland
-> Do Chromophobes (20) produce hormone?
NO!
Figure 86/C. Pituitary gland
- Additionally, the pars intermedia contains small cystic spaces called _____
follicles or cysts of Rathke (25)
Figure 86/C. Pituitary gland
-> Acidophil cells (22) are stained pinkish (their secretory granules are stained with eosin) and are slightly smaller than the basophils.
-> These cells produce ___ (2 hormones)
somatotropin (GH) and prolactin (LTH).
Figure 86/C. Pituitary gland
-> Basophil cells (23) are larger than acidophils and exhibit variable round polyhedral or angular shapes.
-> Their secretory granules are stained ___ (acidophilic/basophilic), hence they appear grey-blue in the specimen.
basophilic!
Figure 86/C. Pituitary gland
-> Basophil cells (23) are larger than acidophils and exhibit variable round polyhe dral or angular shapes. Their secretory granules are stained basophilic, hence they appear grey-blue in the specimen.
=> Name 4 hormones that basophil cells produce
They produce thyrotropin (TSH), follicle-stimulating hormone (FSH), luteinizing hormone (LH) and adrenocorticotropin [ACTH).
Figure 86/C. Pituitary gland
-> The pars intermedia (2) is characterized by ___ (which type of cells?)
Basophilic cells (26) (stained blue)
Figure 86/C. Pituitary gland
-> The pars intermedia (2)
-> The cells can produce __ (Name of hormone?)
They form irregular cellular strands and clumps and produce
melanotropin (MSH).
Figure 86/C. Pituitary gland
- Additionally, the pars intermedia contains small cystic spaces called _____
follicles or cysts of Rathke (25)
Figure 86/C. Pituitary gland
- e pars intermedia contains small cystic spaces called follicles or cysts of Rathke (25), filled with ___
homogeneously stained colloid.
Figure 86/C. Pituitary gland
- The pars intermedia contains small cystic spaces called follicles or cysts of Rathke (25)
-> The follicles are lined by ____
low cuboidal cells, representing the residuum of the Rathke’s pouch.