Vulvar, Vaginal and Ovarian Tumors Flashcards
1
Q
Epidemiology of vulvar cancer
A
- 4-8% of all gynecologicial tumors
- older women
2
Q
Etiology of vuvlvar cancer
A
- poor hygiene
- chronic inflammation
- HPV
3
Q
Histology of vulvar cancer
A
- Planocellular carcinoma
- keratonizing
- nonkeratonizing
- Verrucous carcinoma
4
Q
Symptoms of vulvar cancer
A
- invasion to vagina, anus, urinary meatus, pelvic bones
- discharge, itching, ulcerated
5
Q
Diagnosis of vulvar cancer
A
- inguinal US and pelvic CT/MRI
- palpation of tumors and inguinal lymph node regions
- bimanual rectovaginal examination
- incisional biopsy
6
Q
Radiation therapy for vulvar cancer
A
- postop. RT
- definitive: EBRT if unresectable
7
Q
Surgical therapy for vulvar cancer
A
- surgery is first option
- local wide resection
- radical vulvectomy w/ or w/o adjuvant RT
8
Q
Pharmacological therapy for vulvar cancer
A
cisplatin-5-FU
9
Q
Epidemiology of vaginal cancer
A
- 1-2% of all gynecological tumors
- difficult to diagnose
10
Q
Etiology of vaginal cancer
A
HPV
11
Q
Histology of vaginal cancer
A
- occurs mostly on posterior wall of upper third vagina
- vaginal intraepithelial neoplasia (VAIN): non invasive
- FIGO
12
Q
Symptoms of vaginal cancer
A
- vaginal discharge
- vaginal bleeding
13
Q
Diagnosis of vaginal cancer
A
- physical
- inguinal US
- pelvic CT/MRI
- incisional biopsy
14
Q
Radiotherapy for vaginal cancer
A
- early tumor: definite RT
- advanced tumor: EBRT + brachytherapy (surgery is not an option)
- postop. RT: HDR brachytherapy for stages 1-3
15
Q
Surgical therapy for vaginal cancer
A
- first option for small tumors
- if invasive, similar to therapy for vulva
