Gastric Tumors Flashcards
1
Q
Epidemiology of gastric cancer
A
- higher risk in coal miners
- 10% AC associated with EBV
- adenoid cystic carcinoma
2
Q
Etiology of gastric cancer
A
- helicobacter pylori
- smoked foods
- excess salt intake
3
Q
Histology of gastric cancer
A
glandular epithelium is lacking in diffuse type
4
Q
Symptoms of gastric cancer
A
- asymptomatic
- anemia
- weight loss
- abdominal pain
- lack of appetite
- bloody vomit
- melena
5
Q
Diagnosis of gastric cancer
A
- gastroscopy
- endoscopic US
- CT
- biopsy
6
Q
Radiation therapy for gastric cancer
A
- chemoradiation therapy (adjuvant therapy)
- check HER2 if metastatic and start w/ trastuzumab
- mostly done post-op.
- palliative therapy to stop bleeding
7
Q
Surgical therapy for gastric cancer
A
- curative therapy approach: radical surgery
- T1a: endoscopic mucosal dissection
- T1b, T2-3: surgery
- T3: surgery with preop. therapy
- Sandwich: 3S, surgery, 3S
8
Q
Pharmacological therapy for gastric cancer
A
- periop. for stage 2/3: %FU with platinum, w/ or w/o anthracycline
- adjuvant: same drugs
- tratuzumab for HER2 +
- pembrolizumab for PD1 +
