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PBD II Exam 2 - Micro Made Easy > Viruses II > Flashcards

Viruses II Flashcards

1
Q

negative strand RNA in single strand

  • HA and NA same glycoprotein spike
  • fusion F protein
A

paramyxoviridae

-lungs, kids, viremia

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2
Q

F protein

A

fusion protein

  • causes infected host cells to fuse together
  • in multinucleated giant cells

-paramyxoviridae

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3
Q

parainfluenza virus

A

paramyxoviridae

-rhinitis, pharyngitis, bronchitis

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4
Q

croup

A

parainfluenza infection of larynx
-in children

  • airway narrowing
  • stridor
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5
Q

respiratory syncytial virus

A

paramyxoviridae

  • respiratory infection
  • F protein - causes formation of multinucleated giant cells
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6
Q

number one cause of pneumoniae in children

-especially infants less than 6 months of age

A

respiratory syncytial virus

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7
Q

metapneumovirus

A

paramyxoviridae

  • second most common cause of lower resp infections in young children
  • around 1 year old

-bronchiolitis, croup, pneumonia

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8
Q

mumps virus

A

paramyxoviridae

  • infection of parotid gland
  • orchitis in testes
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9
Q

parotid infection and testes orchitis

A

mumps virus

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10
Q

MMR vaccine

A

measles
mumps
rubella

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11
Q

measles virus

A

paramyxoviridae

  • prodrome syndrome
  • kopliks spots
  • rash
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12
Q

prodrome of measles

A 
conjunctivitis
eyelid swelling
photophobia
high fever
hacking cough
rhinitis
malaise
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13
Q

kopliks spots

A

in measles

  • day or two before rash
  • small red-based lesions with blue-white centers in mouth
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14
Q

small red-based lesions with blue-white centers in mouth

A

kopliks spots

-measles

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15
Q

measles rash

A

red, flat bumpy

  • spreads from forehead to face to neck to torso
  • disappears as it develops
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16
Q

subacute sclerosing panencephalitis

A

slow form of encephalitis
-caused by measles virus

many years after infection- child or adolescent has slow CNS deterioration with incoordination

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17
Q

hepatitis

A

RNA viruses

-infects hepatocytes

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18
Q

fatigue, low grade fever, cough, aches, runny nose, pharyngitis, jaundice, elevated liver enzymes

A

acute viral hepatitis

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19
Q

chronic viral hepatitis

A

patient often asymptomatic with enlarged tender liver and slight elevated liver enzymes

20
Q

hepatocytes produce

A

AST and ALT

21
Q

bile canaliculi produce

A

alkaline phosphatase and GGT

22
Q

viral hepatitis enzymes

A

very high AST and ALT

slightly elevated alkaline phosphatase and GGT

23
Q

bile stone

A

very high alkaline phosphatase and GGT

-bilirubin in blood

24
Q

naked icosahedral with positive single strand RNA

A

hepatitis A virus

  • family picornaviridae
  • fecal-oral transmission
25
Q

hepatitis A virus

A

acute hepatitis

-in youngh children

26
Q

anti-HAV IgM in serum

A

active infection of Hep A

27
Q

anti-HAV IgG in serum

A

old infection of Hep A

28
Q

dane particle

A

intact hepatitis B virus

-large

29
Q

double stranded circular DNA with enveloped icosahedral capsule

A

hepatitis B

  • also has hepatitis B surface antigen
  • HBsAg, HBcAg, and BHeAg
30
Q

HBeAg

A

marker for active disease of hepatitis B

31
Q

anti-HBsAg

A

patient immune against hepatitis B

32
Q

parenteral

A

blood to blood transmission

33
Q

fulminant hepatitis

A

severe acute hepatitis with rapid destruction of liver

-hepatitis B

34
Q

low grade smoldering hepatitis

A

chronic persistent hepatitis

35
Q

chronic active hepatitis

A

acute lasting longer than 6-12 months

36
Q

hepatitis co-infection

A

hepatitis B and hepatitis delta

37
Q

primary hepatocellular carcinoma

A

complication of hepatitis B

200x increased rixk

38
Q

cirrhosis

A

with hepatitis B

39
Q

HBsAg

A

indicates disease state of hepatitis B

40
Q

anti-HBsAg

A

indicates immunity, cure, and no active disease

41
Q

IgM anti-HBcAg

A

new infection

42
Q

IgG anti-HBcAg

A

old infection

43
Q

HBeAg

A

high infectivity of hepatitis B

44
Q

anti-HBeAg

A

low infectivity of hepatitis B

45
Q

relapse of hepatitis B

A

always possible

PBD II Exam 2 - Micro Made Easy (21 decks)

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