Micro - Gram Negative Bacteria I

Question 1

pathogenic gram negative cocci

Answer 1

neisseria

-diplococci

Question 2

neisseria meningitidis

Answer 2

aka meningococcus

causes meningitis and sepsis (meningococcemia)

Question 3

IgA1 protease

Answer 3

in pathogenic neisseria

-cleaves IgA

Question 4

pili attaching to nasopharyngeal cells

Answer 4

in neisseria meningitidis

Question 5

high risk groups for neisseria mengititidis

Answer 5

infants 6 months - 2 years
army recruits
college freshmen

Question 6

army recruits at boot camp get meningitis

Answer 6

neisseria meningitidis

Question 7

college freshman get meningitis

Answer 7

neisseria meningitidis

Question 8

abrupt onset of spiking fever, chills, arthralygia, muscle pain, petechial rash

Answer 8

meningococcemia

Question 9

waterhouse friderichsen syndrome

Answer 9

fulminant meningococcemia

• septic shock
• adrenal insufficiency

abrupt hypotension and tachycardia
-also petechial lesion on skin

Question 10

most common form of meningococcal disease

Answer 10

meningitis in infants less than 1 year

Question 11

bulging anterior fontanelle

Answer 11

sign of meningitis in infants

Question 12

kernig sign

Answer 12

meningitis

Question 13

brudzinskis sign

Answer 13

meningitis

Question 14

thayer martin VCN media

Answer 14

for culturing neisseria

vancomycin - kills gram positives
colistin - kills gram negative except neisseria
nystatin - kills fungis

Question 15

differentiation between neisseria species

Answer 15

meningitis produces acid from maltose

gonorrhoeae cannot

Question 16

gonococcus

Answer 16

neisseria gonorrhoeae

Question 17

gonorrhea

Answer 17

neisseria gonorrheae

second most common STD

Question 18

most common STD

Answer 18

chlamydia

Question 19

virulence factors of gonococcus

Answer 19

pili with variable antigens

outer membrane protein porins - invasion

Opa proteins - adherence nad invasion

Question 20

painful urination with purulent discharge from penis

Answer 20

neisseria gonorrheae

-complications - epididymitis, prostatitis, urethral strictures

Question 21

painful urination and purulent discharge from vagina

Answer 21

neisseria gonorrheae

• infection columnar epithelium of cervix
• can progress to PID - uterus, fallopian tube, ovary inflammation

Question 22

causes of PID

Answer 22

neisseria gonorrhea

chlamydia trachomatis

Question 23

complications of PID

Answer 23

sterility
ectopic pregnancy
abscesses
peritonitis
peri-hepatitis

Question 24

fitz hugh curtis synrome

Answer 24

infection by neisseria gonorrheae of capsule surrounding liver

RUQ tenderness

may follow PID

Question 25

most common septic arthritis in young sexually active individuals

Answer 25

from neisseriae gonorrheae

Question 26

opthalmia neonatorum

Answer 26

eye infection on first or second day of life
-can cause blindess

neisseria gonorrhoeae infection during delivery

Question 27

erythromycin eye drops in newborn

Answer 27

protect against chlamydia and gonorrheae

Question 28

diplococci seen within white blood cells

Answer 28

neisseria gonorrhoeae

Question 29

moraxella catarrhalis

Answer 29

subfamily of neisseriaceae

causes otitis media
and upper respiration infection in patients with COPD or elderly

Question 30

otitis media

Answer 30

middle ear infection by age 3

-common causes:
strep pneumoniae
haemophilus influenza
moraxella catarrhalis

Question 31

kingella kingae

Answer 31

colonizes throat of young children and can cause septic arthritis and osteomyelitis in children

Question 32

cause endocarditis

Answer 32

HACEK
-haemophilus
actinobacillus
cardiobacterium
eikenella
kingella