Virus Lecture 20

Question 1

What DNA virus has reverse transcriptase?

Answer 1

Hepadnaviridae

Question 2

Retro

Answer 2

Reverse/backward reflects the property of retroviruses to use their RNA genome to produce DNA intermediates using reverse transcriptase, an RNA-dependant DNA polymerase

Question 3

What was the first retrovirus described?

Answer 3

Equine infectious anemia

Question 4

What is unique about the retrovirus genome?

Answer 4

Diploid (pseudodiploid), consisting of a dimer of two molecules of linear positive-sense, single-stranded RNA

Question 5

The linear DNA forms integrate into cellular chromosomal DNA as a?

Answer 5

Provirus

Question 6

Oncogenic retrovirus is?

Answer 6

A retrovirus with the gene that has the potential to cause cancer.

Question 7

How is equine infectious anemia transmitted?

Answer 7

Mechanically transmitted through stable fly

Question 8

What does equine infectious anemia infect.

Answer 8

Infects monocytes and macrophages

Question 9

Name the retrovirus in cats?

Answer 9

Feline immunodeficiency virus

Question 10

How is feline immunodeficiency virus transmitted?

Answer 10

Through bite injuries

Question 11

What does feline immunodeficiency virus infect?

Answer 11

Depletion of CD4 positive T helper cells

Question 12

What RNA virus is enveloped, bullet shaped, helically coiled, and nucleocapsid?

Answer 12

Rhabdoviridae

Question 13

What is the genus for Rhabdoviridae?

Answer 13

Lyssavirus

Question 14

What virus is rabies virus?

Answer 14

Rhabdoviridae

Question 15

To diagnose rabies what is looked for?

Answer 15

Infected neurons contain intracytoplasmic inclusion bodies called Negri bodies.

Question 16

What animals get rabies? (according to our teacher)

Answer 16

Dogs, cats, wild canid and felids, vampire bats, mongoose

Question 17

What virus is pleomorphic or filamentous?

Answer 17

Filoviridae: Ebolavirus

Question 18

What is the progression of disease with Filoviridae: Ebolavirus?

Answer 18

Monocyte infection > release of cytokines>endothelial injury>haemorrhage

Question 19

What virus has genomes composed of several (6-8) segemnts of single- stranded RNA?

Answer 19

Orthomyxoviridae

Question 20

What does Orthomyxoviridae cause?

Answer 20

Influenza and Glycoprotein spikes
H=Hemagglutinin (HA)
N=Neuraminidase (NA)

Question 21

For Orthomyxoviridae what is the difference between antigenic shift and antigenic drift?

Answer 21

Antigenic shift is a reassortment of segments of genes

Antigenic drift is a mutation of genes.

Question 22

The Picornaviridae causes what disease in animals and what disease in humans?

Answer 22

Animals: Aphthovirus (foot and mouth)
Humans: Enterovirus (human poliovirus)

Question 23

Which virus is enveloped with spikes called peplomeres?

Answer 23

Coronaviridae

Question 24

What disease are caused by Coronaviridae in cats and humans?

Answer 24

Cats: Feline enteric coronavirus (feline infectious peritonitis virus)
Humans: SARS (Sever acute respiratory syndrome)

Question 25

What virus causes West Nile virus?

Answer 25

Flaviviridae, flavivirus

Question 26

What are the two virus that are arthropod borne?

Answer 26

Flaviviridae and Swine Pox

Question 27

What is the genus name for bovine viral diarrhea virus and classic swine fever in the family Flaviviridae?

Answer 27

Pestivirus

Question 28

Who are dead end hosts for arthropod borne virus?

Answer 28

Humans and horses

Question 29

T:F Bovine viral diarrhea virus is a laten infection.

Answer 29

False

Bovine viral diarrhea virus is a persistent infection.

Question 30

What disease are caused by Togaviridae?

Answer 30

Alphavirus 
Eastern equine encephalitis virus
Western equine encephalitis virus 
Highlands J virus 
Venezuelan equine encephalitis virus

Question 31

What is an arbovirus?

Answer 31

Arthropod borne virus, replicates and transmitted by arthropods

Question 32

What virus causes canine distemper?

Answer 32

Paramyxoviridae