Virus Lecture 19 Flashcards

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1
Q

DNA viruses

A
Poxviridae
Herpesviridae
Papoviridae
Parvoviridae
Adenoviridae
Hepapdnaviridae
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2
Q

T:F The Poxvirus is the only cytoplasmic DNA virus.

A

True

All the others require the nucleus to replicate

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3
Q

What was the first virus eradicated?

A

Poxvirus - the largest and complex animal virus

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4
Q

Chordopoxvirinae effects who?

A

Vertebrates

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5
Q

Entomopoxvirinae effects who?

A

Insects

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6
Q
Groups of important poxvirus:
Avipoxvirus
Capripoxvirus
Cervidpoxvirus
Leporipoxvirus 
Molluscipoxvirus
A
Avian
Goat
Deer
Rabbits 
Horse
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7
Q

Variolation is?

A

The process of vaccination

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8
Q

Adsorption and penetration of the poxvirus is done by?

A

Binding to the cell surface receptors. It enters via endocytosis or by the direct fusion. The virus is released minus its envelope.

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9
Q

What disease dose the Poxvirus cause

A
Lumpy skin disease in cattle
Ectromelia (self-amputation) in rodents
Rabbid Myxoma (neoplastic transformation) in rabbits
Parapox or Orf in sheep
Swine Pox
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10
Q

What is the pox virus characterized by?

A

Intracytoplasmic inclusion bodies

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11
Q

Which is the most dangerous animal pox?

A

Swine Pox - it is transmitted by biting louse

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12
Q

Can the poxvirus species jump?

A

Yes; Cow pox in cats

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13
Q

Where dies the Parvovirus replicate?

A

In the nucleus and produce intranuclear inclusion bodies

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14
Q

Can Parvovirus replicate autonomously?

A

Yes ONLY in actively cycling cells. Otherwise, co-infection with either an adenovirus or a Herpesvirus is necessary.

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15
Q

T:F The Parvovirus is not every stable because of no envelope.

A

False

It is very stable virus (No envelope)

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16
Q

T:F Some Parvovirus contain only the negative-sense DNA strand

A

True

17
Q

Parvovirus infections of the fetus or newborn result in?

A

Widespread infection and tissue destruction that cause developmental defects

18
Q

T:F Parvoviruses require cycling cells for virus replication.

A

True

19
Q

What is the receptor for canine parvovirus and feline panleukopenia virus?

A

Transferrin

20
Q

What is the disease caused by the parvovirus in cats?

A

Feline panleukopenia virus

21
Q

What does feline panleukopenia virus cause?

A

Cerebellar hypoplasia

22
Q

Why does parvovirus effect the young?

A

It infects and destructs rapidly dividing cells of the villi of the GI tract.

23
Q

Which is the DNA virus that is associated with cell histones (nucleosomes)?

A

Papilloma virus

24
Q

What is Papilloma virus known to cause?

A

Warts and cervical cancer.

25
Q

What is the non-enveloped, icosahedral viruses with fibers at vertices?

A

Adenovirus

26
Q

What does canine adenovirus cause?

A

Infectious canine hepatitis

Infectious canine bronchitis - Kennel cough

27
Q

Which DNA virus is the most widespread effecting virus?

A

Herpesvirus

28
Q

Herpesvirus can sometimes alternate host species called?

A

Species-Jumping

29
Q

Where does DNA replication and encapsidation occur in herpesvirus?

A

Nucleus

30
Q

What is a herpesvirus infection characterized by?

A

Eosinophilic intranuclear inclusion bodies

31
Q

Herpesvirus species jumping from porcine herpesvirus to?

A

Pseudorabies in dogs