Virus Lecture 19 Flashcards
DNA viruses
Poxviridae Herpesviridae Papoviridae Parvoviridae Adenoviridae Hepapdnaviridae
T:F The Poxvirus is the only cytoplasmic DNA virus.
True
All the others require the nucleus to replicate
What was the first virus eradicated?
Poxvirus - the largest and complex animal virus
Chordopoxvirinae effects who?
Vertebrates
Entomopoxvirinae effects who?
Insects
Groups of important poxvirus: Avipoxvirus Capripoxvirus Cervidpoxvirus Leporipoxvirus Molluscipoxvirus
Avian Goat Deer Rabbits Horse
Variolation is?
The process of vaccination
Adsorption and penetration of the poxvirus is done by?
Binding to the cell surface receptors. It enters via endocytosis or by the direct fusion. The virus is released minus its envelope.
What disease dose the Poxvirus cause
Lumpy skin disease in cattle Ectromelia (self-amputation) in rodents Rabbid Myxoma (neoplastic transformation) in rabbits Parapox or Orf in sheep Swine Pox
What is the pox virus characterized by?
Intracytoplasmic inclusion bodies
Which is the most dangerous animal pox?
Swine Pox - it is transmitted by biting louse
Can the poxvirus species jump?
Yes; Cow pox in cats
Where dies the Parvovirus replicate?
In the nucleus and produce intranuclear inclusion bodies
Can Parvovirus replicate autonomously?
Yes ONLY in actively cycling cells. Otherwise, co-infection with either an adenovirus or a Herpesvirus is necessary.
T:F The Parvovirus is not every stable because of no envelope.
False
It is very stable virus (No envelope)
T:F Some Parvovirus contain only the negative-sense DNA strand
True
Parvovirus infections of the fetus or newborn result in?
Widespread infection and tissue destruction that cause developmental defects
T:F Parvoviruses require cycling cells for virus replication.
True
What is the receptor for canine parvovirus and feline panleukopenia virus?
Transferrin
What is the disease caused by the parvovirus in cats?
Feline panleukopenia virus
What does feline panleukopenia virus cause?
Cerebellar hypoplasia
Why does parvovirus effect the young?
It infects and destructs rapidly dividing cells of the villi of the GI tract.
Which is the DNA virus that is associated with cell histones (nucleosomes)?
Papilloma virus
What is Papilloma virus known to cause?
Warts and cervical cancer.
What is the non-enveloped, icosahedral viruses with fibers at vertices?
Adenovirus
What does canine adenovirus cause?
Infectious canine hepatitis
Infectious canine bronchitis - Kennel cough
Which DNA virus is the most widespread effecting virus?
Herpesvirus
Herpesvirus can sometimes alternate host species called?
Species-Jumping
Where does DNA replication and encapsidation occur in herpesvirus?
Nucleus
What is a herpesvirus infection characterized by?
Eosinophilic intranuclear inclusion bodies
Herpesvirus species jumping from porcine herpesvirus to?
Pseudorabies in dogs
