BacT lecture 6 Flashcards

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1
Q

Which is the non-sporing Gram-poistive bacteria that is not a species?

A

Listeria

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2
Q

What is Listeria?

A

Listeria momcytogens- a facultatlive intracellular bacterium that is a food born pathogen commonly in silage that causes septicemia, abortion, meninoencephlitis.

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3
Q

How does Listeria momcytogens evade phagocytes?

A

Through the use of actin filaments to travel through the cell (intimin)

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4
Q

What is the Gram-pos bacteria that causes diamond skin disease in swine?

A

Erysipelothrix rhusiopathiae

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5
Q

What is Erysipelothrix rhusiopathiae?

A

Gram-pos bacteria sine erysipela, septicemic disease, high mortality in turkey, Zoonotic, humans and dolphins.

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6
Q

What are the Mycobacterium?

A

Acid fast positive, Intracellular (factltative obligate parasites)

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7
Q

What are two species of Mycobacterium and what do they cause?

A

M. tuberculisis (humans tuberculosis)
M. bovis (bovine tuberculosis - induce granulomas)
M. avium subsp. avium (avian tuberculosis)
M. avium subsp. patatuberculosis -Johne’s disease (cattle, sheep, goats)

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8
Q

What does the lymph nodes look like from Mycobacterium?

A

Large and yellow in color

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9
Q

In M. avium subsp. patatuberculosis what does it cause and what do we think it may be connected to?

A

Known as Johne’s disease causes chronic granulomatous enteritis. May be linked to Crohn’s disease

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10
Q

Gram-negative rods are

A

Faculatively anaerobic
Family name Enterobacteriaceae
Important genera are Escherichia, Salmonella, Yersinia

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11
Q

Enterobacteriaceae

A

Gram-neg oxidase negative rods, ferment glucose, motile. Normal part of microflora in intestinal tract.

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12
Q

Which Enterobacteriaceae that is a lactose positive bacteria is used to evaluate fecal contamination?

A

Coliform bacteria (E. coli, Klebsiella, Enterobacter)

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13
Q

Important faecal bacteria in public health

A
Coliform bacteria (E. coli, Klebsiella, Enterobacter)
Faecal Streptococcus and enterococcus
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14
Q

T:F the bacteria that are used as indicator bacteria of fecal contamination are harmful themselves.

A

False

They suggest that pathogenic microorganisms might also be present.

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15
Q

The US Environmental Protection Agency (EPA) recommends the use of what bacteria because it is more human specific.

A

Enterococcus (even tho not Enterobacteriaceae)

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16
Q

What is the only pathogenic bacteria for family Enterobacteriaceae genera Escherichia?

A

E. Coli - some strains cause important disease of domestic animals

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17
Q

What are the frankly pathogenic bacteria generas of family Enterobacteriaceae?

A

Salmonella
Shigella
Yersinia

18
Q

What are the mostly opportunists bacteria generas of family Enterobacteriaceae?

A
Klebsiella
Proteus
Serratia
Enterobacter
Citrobacter
19
Q

What are the Gram-neg general virulence factors?

A
Endotoxin
Capsule
Siderophores
Exotoxins
Flagella
Adhesion Factors: Fimbriae, pili, colonizing factors antigen
20
Q

How are genus Escherichia E. coli characterized?

A

By the O polysaccharides components of the LPS and phagonistic capacity.

21
Q

What are the main types of E. coli?

A
Enterotoxinogenic (ETEC)
Enteropathogenic (EPEC)
Enteroinvasive (EIEC)
Enterohemorrhagic (EHEC)
Extraintestinal pathogenic E. Coli (ExtEC)
22
Q

What does Enterotoxinogenic E. coli cause?

A

Diarrhea in humans (travelers diarrhea) and neonatal colisepticemia in calves and pigs.

23
Q

Why does Enterotoxinogenic E. coli only cause colisepticemia in young animals?

A

Receptors for adhesion are only present for the first week of life in calves and the first six weeks of life in piglets.
K88 (F4) - piglets
K99 (F5) - calves

24
Q

What are some of the virulence factors for Enterotoxinogenic E. coli?

A

Two enterotoxins that are heat stable and heat labile toxins.
They are exotoxins and AB toxins

25
Q

What is another name of the Enterohemorragic E. coli?

A

Shega toxin producing E. coli

26
Q

Why is Enterohemorragic E. coli named Shega toxin producing E. coli?

A

It produces Shiga like toxins (verotoxins)

27
Q

What does Enterohemorragic E. coli cause?

A

Edina disease in piglets

Hemorrhagic enteritis and Hemolytic uremic syndrome in humans

28
Q

What are the two salmonella species we have to know?

A

Salmonella enterica

Salmonella bongori

29
Q

Which Salmonella species has over 2500 serotypes?

A

Salmonella enterica subsp enterica

30
Q

What is unique about Salmonella enterica subsp enterica?

A

The serotypes are named like species, but are actually not.

31
Q

What are some host specific serovars of Salmonella enterica subsp enterica?

A

Salmonella dublin - cattle
Salmonella typhi - humans
Salmonella enteritidis- chickens & humans

32
Q

What does Salmonella enterica subsp enterica cause?

A

Animals: septicemia and acute, subacute and chronic enteritis
Humans: principally gastroenteritis, enteric fever (typhoid) and septicemia

33
Q

What is the difference in Salmonella typhoid and enteric

A

Typhoid is human only and is systemic disease of bacterial invasion of the blood stream.
Enteric is animal and humans restricted to intestinal tract from foodborne infection/intoxication

34
Q

What are the three species of genus Yersinia?

A

Yersinia enterocolitica
Yersinia pseudotuberculosis
Yersinia pestis

35
Q

What is Yersinia enterocolitica known for?

A

It is a pathogen of both animals and humans causes gastroenteritis and other infections.

36
Q

What is Yersinia pseudotuberculosis know for?

A

Mainly an animal pathogen - causes acute enteric disease

37
Q

What is Yersinia pestis known for?

A

Causes Plague in humans, rodents and cats (Zoonotic)

38
Q

What are the three forms of Plague?

A
Septicemic (infects blood)
Bubonic plague (infects lymph nodes)
Pneumonic plague (infects respiratory tract)
39
Q

Which of the three forms of Plague is the black death

A

Bubonic plague

40
Q

How does Yersinia pestis work?

A

Usually found in small animals and their fleas. Transmitted between animals and humans by the bite of infected fleas, direct contact, inhalation and rarely ingestion of infective materials