Virology Intro

Question 1

Capsid

Answer 1

Empty shell like structure composed of protein subunits (capsomers)

Question 2

Nucleocapsid

Answer 2

Viral nucleic acid enclosed inside the capsid

Question 3

Capsomer

Answer 3

Group of proteins that come together to form one protein unit. A collection forms helical, icosohedral/polyhedral, complex

Question 4

Envelope

Answer 4

A lipid rich outer membrane layer, covering nucleocapsid
Only found on some viruses
Usually obtained from host cell membrane
May help to — avoid host immune response, protection

Question 5

Peplomers/Spikes

Answer 5

Protrude from surface of the virus envelope

Role — attach to host cell, viral entry and exit, infectivity, cell specificity

Question 6

Nucleic acid

Answer 6

Can have DNA or RNA
Unique purine and/or pyrimidine bases
Can be linear, circular, or in separate segments

Question 7

Prodromal phase

Answer 7

Early nonspecific symptoms before more specific disease symptoms

Question 8

Chronic infection

Answer 8

Continuation of primary infection
Most commonly fatal
Persistent recovery of virus with immunopathology

Question 9

Latent infection

Answer 9

Dormant virus
Virus within the host not producing immunopathology
May or may not be producing active virus, showing no symptoms of infection

Question 10

Prion

Answer 10

Proteinaceous infectious particle or Transmissible spongiform encephalitis