Parasites - Blood Protozoa Flashcards
Plasmodium vivax info
splenic rupture
only infects reticulocytes - low parasitic burden
Shuffners dots
Plasmodium falciparum info
infects any stage of RBC most common most severe most deadly Maurers dots
Plasmodium ovale info
only infected reticulocytes - low burden
trophs with single chromatin dot - Shuffners dots, fimbriation
smaller than P vivax, elongated to oval shape
Plasmodium malariae info
infects mature RBC
trophs thicker than P falciparum - band formation during maturation
Ziemans stippling
Plasmodium knowlesi info
most commonly in macaques, rare human infection
Plasmodium species infectious stage
Mosquito takes a blood meal (injects sporozoites)
Release of sporozoites
Plasmodium species diagnostic stage
Immature trophozoite (ring stage)
Mature trophozoite
Schizont
Gametocytes
Babesia infectious stage
Sporozoites
Tick takes a blood meal (sporozoites introduced into host)
Babesia diagnostic stage
Sporozoites enter erythrocytes and undergo asexual replication (budding)
Babesia info
merozoite stage = Maltese cross (pathognomonic)
Trypanosoma brucei infectious stage
Tsetse fly takes a blood meal (injects metacyclic trypomastigote)
Trypanosoma brucei diagnostic stage
Circulating trypomastigotes in blood during acute phase - Usually undetectable in latent phase
Trypanosoma brucei info
elongated body with posterior flagellum
central nucleus with posterior kinetoplast
buffy coat smear best for diagnosis
Trypanosoma brucei symptoms
Gambain - neurologic deterioration (chronic)
Rhodesia - rapid onset leading to possible death (acute, rapid)
Winterbottoms sign
invasion of CNS
Trypanosoma brucei classification
African sleeping sickness
Blood protozoa - Hemoflagellate
Trypanosoma cruzi infectious stage
Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in feces, enter bite wound or mucosal membrane, such as the conjunctiva)
Trypanosoma cruzi diagnostic stage
Intracellular amastigotes transform into trypomastigotes, then burst out of the cell and enter the bloodstream
Trypanosoma cruzi info
nocturnal and feed on sleeping victims
found in form of a āCā
reservoirs - dogs and raccoons
Trypanosoma cruzi classification
Chagas disease
South American trypanosomiasis
Blood protozoa - hemoflagellate
Primary cutaneous Leishmaniasis infectious stage
Sandfly takes a blood meal (injects promastigote stage into the skin)
Primary cutaneous Leishmaniasis diagnostic stage
Promastigotes transform into amastigotes
Amastigotes multiplying cells of various tissues and infect other cells
Visceral Kala Azar infectious stage
Sandfly takes a blood meal (injects promastigote stage into the skin)
Visceral Kala Azar infectious stage
Promastigotes transform into amastigotes
Amastigotes multiplying cells of various tissues and infect other cells
