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IMMUNOLOGY > VIROLOGY > Flashcards

VIROLOGY Flashcards

1
Q

chronic infections is

A

virus detachable in tissues sample multiplying slowly, symptoms mild or absences

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2
Q

latency infections is

A

virus enters a dormant phase, no symptoms can reactive

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3
Q

what is teratogenic ?

A

several viruses can cross placenta causing development disturbance and permanent defects

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4
Q

envelope ds virus that hv glcoproteins surrounding it includes

A

poxvirus, herpesvirus, hepadanavirus

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5
Q

nonenvelope ds virus examples :

A

adenoviruses

polymaviruses/papilomaviruses

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6
Q

paroviruses are

A

non envelope ss genome

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7
Q

poxvirus transmitted thru ?

A

inhalation or skin contact

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8
Q

infection associated w fever, malaise, prostration and rash is symptoms of

A

smallpox

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9
Q

variola major -

variola minor -

A

highly virulent caused toxemia, shock and intravascular coagulation
less virulent

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10
Q

HSV 1 -usually lesion on the oropharynx , cold sores, fever blisters affect

A

early childhood

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11
Q

HSVV 2-lesions in genitalia , oral

A

ages 14-29

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12
Q

HSV 1 mainly transmitted thru ?

A

oral secretions in close non-sexual contact (touch, kisss , share food)

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13
Q

HSV 1 types :

A

herpes labialis -fever blisters, cold sores, itchiness
herpetic gingivostomatitis -infection of oropharynx in young children
herpetic keratinis -ocular herpes, inflammation of eye

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14
Q

herpes reactivation is triggered by

A

stress, uv radiation, mechanical injury

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15
Q

HSV multiples in sensory neurons moves to ganglia
HSV 1 enters 5th cranial nerve
HSV 2 enters ________

A

lumbrosacral spinal nerve trunk ganglia

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16
Q

HSV 2 primarily associated with genital infections and lesion can be found at

A

vulva, vagina, cervix, urethra, perineum, penis, rectum

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17
Q

Malaise, anorexia fever, bilateral swelling and tenderness in groin , itchiness, painful urination is lead to ______

A

herpes genitalia

18
Q

Genital and neonatal herpes can be transmitted thru hand transmission and affecting mouth, skin, eyes, how to prevent ?

A

screening of pregnant women

delivery by c section

19
Q

herpetic whitlows is

A

HSV 1&2 that penetrate a break in skin and cause localized infection on one fingers

20
Q

herpes simplex hv giant cell with multiple nuclei , it can be treated by

A

acyclovir, famiciclovir, valacyclovir, topical medications

21
Q

varicella zoster virus (VZN) causes

A

chickenpox and shingles transmitted thru respiratory droplets and contact

22
Q

cytomegalovirus (CMV) produce giant cell w nuclear and cytoplasmic inclusions that transmitted thru

A

saliva, respiratory mucus, milk , urine, semen, cervical secretions&feces

23
Q

enlarged liver, spleen, jaundice, capillary bleeding microcephaly and ocular inflammation is caused by

A

cytomegaloviruse (CMV)

24
Q

perinatal CMV infection is mostly asymptomatic and hv _____

A

mononucleosislike syndrome

25
Q

epstein barr virus (EBV) infects lymphoid tissue and salivary glands and causes

A

infectious mononucleosis -sore throat , high fever,cervical lymphadenopathy

26
Q

complications associated w EBV are

A

burkitt lymphoma - B cells malignancy usually develops in jaw and grossly swells th cheeck
nasopharyngeal carcinoma - malignancy of epithelial cells

27
Q

EBV can be treated by

A

IV gamma globulin, interferon, acylovir, monoclonal antibodies

28
Q

Hepadnaviruses caused

A

hepatitis

29
Q

what is hepatitis ?

A

inflammation of the liver cause liver scarring/ cirrhosis

30
Q

what is DNA virus hepatitis ?

A

hepatitis b

31
Q

symptoms of hepatitis

A

jaundice abdominal pain , dark tea coloured urine, pale clay coloured stool, edema , bleeding

32
Q

drug addict and homosexual most likely to get

A

hepatitis B transmitted sexually, blood

33
Q

Non envelope DNA virus is _____

A

adenoviruses

34
Q

adenoviruses is transmitted thru respiratory and ocular secretions what does it causes ?

A

colds, pharyngitis, conjuctivitis, keratoconjuctivities, acure hemorrhagic cystitis

35
Q

adenovirus is treated with

A

iinterferon

36
Q

papiloma and polynoma is nonenveloped ds DNA, what is papiloma ?

A

squamous epithelial growth, wart or veruca

37
Q

different strain of HPV ?

A

seed warts -painless, elevated,rough growth on fingers
plantar warts - deep painful in soles of feet
genital warts - STD, morphology ranges from tiny,flat, inconspious bumps to extensive, cauliflower like masses

38
Q

HPV is transmitted thru ?

A

direct contact or contaminated formites

39
Q

pap smear screen abnormal cervical cells when the patient hv abnorml vaginal discharge and pain. what is the disease /?

A

cervical cancer

40
Q

HPV can be treated by

A

safe sexual practice
laser surgery
vaccine
removed by direct chemical application of podophyllin and physical removal by cauterization

IMMUNOLOGY (19 decks)

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