VIROLOGY

Question 1

chronic infections is

Answer 1

virus detachable in tissues sample multiplying slowly, symptoms mild or absences

Question 2

latency infections is

Answer 2

virus enters a dormant phase, no symptoms can reactive

Question 3

what is teratogenic ?

Answer 3

several viruses can cross placenta causing development disturbance and permanent defects

Question 4

envelope ds virus that hv glcoproteins surrounding it includes

Answer 4

poxvirus, herpesvirus, hepadanavirus

Question 5

nonenvelope ds virus examples :

Answer 5

adenoviruses

polymaviruses/papilomaviruses

Question 6

paroviruses are

Answer 6

non envelope ss genome

Question 7

poxvirus transmitted thru ?

Answer 7

inhalation or skin contact

Question 8

infection associated w fever, malaise, prostration and rash is symptoms of

Answer 8

smallpox

Question 9

variola major -

variola minor -

Answer 9

highly virulent caused toxemia, shock and intravascular coagulation
less virulent

Question 10

HSV 1 -usually lesion on the oropharynx , cold sores, fever blisters affect

Answer 10

early childhood

Question 11

HSVV 2-lesions in genitalia , oral

Answer 11

ages 14-29

Question 12

HSV 1 mainly transmitted thru ?

Answer 12

oral secretions in close non-sexual contact (touch, kisss , share food)

Question 13

HSV 1 types :

Answer 13

herpes labialis -fever blisters, cold sores, itchiness
herpetic gingivostomatitis -infection of oropharynx in young children
herpetic keratinis -ocular herpes, inflammation of eye

Question 14

herpes reactivation is triggered by

Answer 14

stress, uv radiation, mechanical injury

Question 15

HSV multiples in sensory neurons moves to ganglia
HSV 1 enters 5th cranial nerve
HSV 2 enters ________

Answer 15

lumbrosacral spinal nerve trunk ganglia

Question 16

HSV 2 primarily associated with genital infections and lesion can be found at

Answer 16

vulva, vagina, cervix, urethra, perineum, penis, rectum

Question 17

Malaise, anorexia fever, bilateral swelling and tenderness in groin , itchiness, painful urination is lead to ______

Answer 17

herpes genitalia

Question 18

Genital and neonatal herpes can be transmitted thru hand transmission and affecting mouth, skin, eyes, how to prevent ?

Answer 18

screening of pregnant women

delivery by c section

Question 19

herpetic whitlows is

Answer 19

HSV 1&2 that penetrate a break in skin and cause localized infection on one fingers

Question 20

herpes simplex hv giant cell with multiple nuclei , it can be treated by

Answer 20

acyclovir, famiciclovir, valacyclovir, topical medications

Question 21

varicella zoster virus (VZN) causes

Answer 21

chickenpox and shingles transmitted thru respiratory droplets and contact

Question 22

cytomegalovirus (CMV) produce giant cell w nuclear and cytoplasmic inclusions that transmitted thru

Answer 22

saliva, respiratory mucus, milk , urine, semen, cervical secretions&feces

Question 23

enlarged liver, spleen, jaundice, capillary bleeding microcephaly and ocular inflammation is caused by

Answer 23

cytomegaloviruse (CMV)

Question 24

perinatal CMV infection is mostly asymptomatic and hv _____

Answer 24

mononucleosislike syndrome

Question 25

epstein barr virus (EBV) infects lymphoid tissue and salivary glands and causes

Answer 25

infectious mononucleosis -sore throat , high fever,cervical lymphadenopathy

Question 26

complications associated w EBV are

Answer 26

burkitt lymphoma - B cells malignancy usually develops in jaw and grossly swells th cheeck
nasopharyngeal carcinoma - malignancy of epithelial cells

Question 27

EBV can be treated by

Answer 27

IV gamma globulin, interferon, acylovir, monoclonal antibodies

Question 28

Hepadnaviruses caused

Answer 28

hepatitis

Question 29

what is hepatitis ?

Answer 29

inflammation of the liver cause liver scarring/ cirrhosis

Question 30

what is DNA virus hepatitis ?

Answer 30

hepatitis b

Question 31

symptoms of hepatitis

Answer 31

jaundice abdominal pain , dark tea coloured urine, pale clay coloured stool, edema , bleeding

Question 32

drug addict and homosexual most likely to get

Answer 32

hepatitis B transmitted sexually, blood

Question 33

Non envelope DNA virus is _____

Answer 33

adenoviruses

Question 34

adenoviruses is transmitted thru respiratory and ocular secretions what does it causes ?

Answer 34

colds, pharyngitis, conjuctivitis, keratoconjuctivities, acure hemorrhagic cystitis

Question 35

adenovirus is treated with

Answer 35

iinterferon

Question 36

papiloma and polynoma is nonenveloped ds DNA, what is papiloma ?

Answer 36

squamous epithelial growth, wart or veruca

Question 37

different strain of HPV ?

Answer 37

seed warts -painless, elevated,rough growth on fingers
plantar warts - deep painful in soles of feet
genital warts - STD, morphology ranges from tiny,flat, inconspious bumps to extensive, cauliflower like masses

Question 38

HPV is transmitted thru ?

Answer 38

direct contact or contaminated formites

Question 39

pap smear screen abnormal cervical cells when the patient hv abnorml vaginal discharge and pain. what is the disease /?

Answer 39

cervical cancer

Question 40

HPV can be treated by

Answer 40

safe sexual practice
laser surgery
vaccine
removed by direct chemical application of podophyllin and physical removal by cauterization