GRAM - BACTERIA Flashcards

1
Q

the only gram - cocci is ____

A

neisseria

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2
Q

neisseria meningitis can ferments glucose and maltose (T/F)

A

trueee

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3
Q

what neisseria gonorrohea fements ?

A

glucose

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4
Q

two types of neisseria :

A

gonorrhea

meningitis

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5
Q

2 types of aerobe bacilli is

A

bordetella

heamophilus

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6
Q

obligate aerobe bacili is

A

pseudomonas (green pigments)

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7
Q

facultative bacili types include :

A
lactose fermenter - ecoli
capsule
non lactose fermenter -
salmonella (typhoid)
shingels (dysentary)
proteus (UTI)
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8
Q

neisseria meningitits virulence factors ?

A

polysaccharide capsule leads to meningitis

asymptomatic normal flora in body

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9
Q

neisseria gonorrohoe virulence factors ?

A

pili adhere , antiphagocytic

hv outer membrane proteins

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10
Q

neisseria gonorrohoe is sexually transmitted what is the diseases ?

A

urethritis,pelvic inflammatory disease in women

opthalia neonatal, conjuctivitis

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11
Q

rifampin , penicilin G , vaccine is used to treat ?

A

meningitis by neisseria meningitis

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12
Q

gram + diploccoci ?

A

s. viridins

s. pneumonia

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13
Q

salmonella typhi cause what disease?

A

thyphoid fever/enteric fever that spread in animal to human

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14
Q

salmonella typi and paratypi ABC can be cultured in ?

A

macconkey : colourless

wilson blair bismuth sulphide produce black colonies

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15
Q

o antigen virulence factor of salmonella is _____ immunogenic than H antigen

A

less it act llike endotoxin and unaffected y boiling (heat stable)

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16
Q

Vi antigen is polysaccharide what its fx

A

prevents agglutination, destroy after boiling at 6oc

17
Q

protects the bacilli against phagocytosis and poorly immunogenic what its virulence factor

A

Vi antigen

18
Q

rashes in typhoid located at ?

A

front of chest that loook like rose spots irregular blanching pink maculae

19
Q

pathology of salmonella

A
enter thru ingestion
attach to microvili
penetrate lamina propria and sub mucosa
phagocytosis by polymorphes, macrophages
enters mesenteric lymph nodes
enter the throcic duct-blood stream
enters kidney gallbladder liver GIT cause necrosis
typhoid ulcer occurs
20
Q

salmonella gastroenteritis is nontyphoidal salmonella what is the symptoms?

A

abdominal pain mucous , bloody diarrhea, vomitting

21
Q

e coli can be transmitted thru

A

fecal-oral strains

22
Q

4 types of pathogenic strains
HP - large intestine
IT -small intestine

A

enterohaemorrhagic e coli (EHEC) -large intestine
enterotoxigenic e coli (ETEC) - small intestine
enteroinvasive e coli ( EIEC) - large intestine
enteropathogenic e coli (EPEC) -small intestine

23
Q

EHEC produce cytotoxins that disrupt protein synthesis within host cellsn, what is the toxxin called?

A

verocytotoxin (form attaching and effacing lessions on epithelial cells), shinga like toxin

24
Q

what is EHEC complications ?

A

haemolytic uremic syndrome

25
ETEC disease includes ?
travelers diarrhoea , watery diarrhae, nausea, headache
26
colonization factor antigens in small intestine is virulence factor of _____
enterotoxigenic e coli (heat stable , heat labile)
27
EIEC charaterictis is
ability to induce entry into epithelial cells and disseminate from cell to cell
28
EIEC mot
contaminated food / water or thru mechanical factors
29
how EIEC cause dysentery ?
organism invade the epithelial cells during ingestion
30
EPEC diseases
watery diarhea or bloody
31
EPEC pathogenesis mechanism
involve formation of attaching and effacing lesions followed by interference with host cell signal transduction
32
what bacteria resitant to multiple drugs ?
pseudomonas aeruginosa (gram - rods motile obligate aerobe )
33
pseudomonas aeruginosa can be from ____
infected wound, burns, nails, nnecrotizing pneumoniae ,corneal ulcer, otitis externa, urinary tract
34
greenish blue colonies and sweet odor of p. aeruginosa is from ______
pyocyanin -nonfluroscent bluish pyoverdin -fluorescent greenish pyorubin, pyomelanin - hv polyssacharide capsule
35
vibrio cholera virulence factors
flagellum (H antigen) mucinase -digest mucous layer to attach to cells fimbriae -helps w attachment to other cell noninvasive
36
clinical manifestation of vibrio cholera
cholera - diarhrea w rice water stool no pus muscle cramps circulatory shock/collapse
37
vibrio cholera can be transmitted thru fecal oral and can ferments sugar except
lactose
38
helicobacter pylori virulence factor :
adhesins- fimbriae enzymes - urease, protease, cytokines toxins -cytoxins