GRAM - BACTERIA Flashcards

1
Q

the only gram - cocci is ____

A

neisseria

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2
Q

neisseria meningitis can ferments glucose and maltose (T/F)

A

trueee

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3
Q

what neisseria gonorrohea fements ?

A

glucose

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4
Q

two types of neisseria :

A

gonorrhea

meningitis

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5
Q

2 types of aerobe bacilli is

A

bordetella

heamophilus

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6
Q

obligate aerobe bacili is

A

pseudomonas (green pigments)

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7
Q

facultative bacili types include :

A
lactose fermenter - ecoli
capsule
non lactose fermenter -
salmonella (typhoid)
shingels (dysentary)
proteus (UTI)
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8
Q

neisseria meningitits virulence factors ?

A

polysaccharide capsule leads to meningitis

asymptomatic normal flora in body

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9
Q

neisseria gonorrohoe virulence factors ?

A

pili adhere , antiphagocytic

hv outer membrane proteins

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10
Q

neisseria gonorrohoe is sexually transmitted what is the diseases ?

A

urethritis,pelvic inflammatory disease in women

opthalia neonatal, conjuctivitis

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11
Q

rifampin , penicilin G , vaccine is used to treat ?

A

meningitis by neisseria meningitis

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12
Q

gram + diploccoci ?

A

s. viridins

s. pneumonia

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13
Q

salmonella typhi cause what disease?

A

thyphoid fever/enteric fever that spread in animal to human

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14
Q

salmonella typi and paratypi ABC can be cultured in ?

A

macconkey : colourless

wilson blair bismuth sulphide produce black colonies

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15
Q

o antigen virulence factor of salmonella is _____ immunogenic than H antigen

A

less it act llike endotoxin and unaffected y boiling (heat stable)

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16
Q

Vi antigen is polysaccharide what its fx

A

prevents agglutination, destroy after boiling at 6oc

17
Q

protects the bacilli against phagocytosis and poorly immunogenic what its virulence factor

A

Vi antigen

18
Q

rashes in typhoid located at ?

A

front of chest that loook like rose spots irregular blanching pink maculae

19
Q

pathology of salmonella

A
enter thru ingestion
attach to microvili
penetrate lamina propria and sub mucosa
phagocytosis by polymorphes, macrophages
enters mesenteric lymph nodes
enter the throcic duct-blood stream
enters kidney gallbladder liver GIT cause necrosis
typhoid ulcer occurs
20
Q

salmonella gastroenteritis is nontyphoidal salmonella what is the symptoms?

A

abdominal pain mucous , bloody diarrhea, vomitting

21
Q

e coli can be transmitted thru

A

fecal-oral strains

22
Q

4 types of pathogenic strains
HP - large intestine
IT -small intestine

A

enterohaemorrhagic e coli (EHEC) -large intestine
enterotoxigenic e coli (ETEC) - small intestine
enteroinvasive e coli ( EIEC) - large intestine
enteropathogenic e coli (EPEC) -small intestine

23
Q

EHEC produce cytotoxins that disrupt protein synthesis within host cellsn, what is the toxxin called?

A

verocytotoxin (form attaching and effacing lessions on epithelial cells), shinga like toxin

24
Q

what is EHEC complications ?

A

haemolytic uremic syndrome

25
Q

ETEC disease includes ?

A

travelers diarrhoea , watery diarrhae, nausea, headache

26
Q

colonization factor antigens in small intestine is virulence factor of _____

A

enterotoxigenic e coli (heat stable , heat labile)

27
Q

EIEC charaterictis is

A

ability to induce entry into epithelial cells and disseminate from cell to cell

28
Q

EIEC mot

A

contaminated food / water or thru mechanical factors

29
Q

how EIEC cause dysentery ?

A

organism invade the epithelial cells during ingestion

30
Q

EPEC diseases

A

watery diarhea or bloody

31
Q

EPEC pathogenesis mechanism

A

involve formation of attaching and effacing lesions followed by interference with host cell signal transduction

32
Q

what bacteria resitant to multiple drugs ?

A

pseudomonas aeruginosa (gram - rods motile obligate aerobe )

33
Q

pseudomonas aeruginosa can be from ____

A

infected wound, burns, nails, nnecrotizing pneumoniae ,corneal ulcer, otitis externa, urinary tract

34
Q

greenish blue colonies and sweet odor of p. aeruginosa is from ______

A

pyocyanin -nonfluroscent bluish
pyoverdin -fluorescent greenish
pyorubin, pyomelanin - hv polyssacharide capsule

35
Q

vibrio cholera virulence factors

A

flagellum (H antigen)
mucinase -digest mucous layer to attach to cells
fimbriae -helps w attachment to other cell
noninvasive

36
Q

clinical manifestation of vibrio cholera

A

cholera - diarhrea w rice water stool no pus
muscle cramps
circulatory shock/collapse

37
Q

vibrio cholera can be transmitted thru fecal oral and can ferments sugar except

A

lactose

38
Q

helicobacter pylori virulence factor :

A

adhesins- fimbriae
enzymes - urease, protease, cytokines
toxins -cytoxins