IMMUNE SYSTEM Flashcards
body defence mechanism is
WBC include granulocyte, lymphocyte, leukocyte, monocyte
b cell will matured and become
plasma cells
pluripotent stem cell have
myeloid lineage lymphoid lineage
myeloid lineage have 3types
granulocyte precusor -neutrophil, baso
monoblast -macrophage
dendritic cells
lymphoid lineage have 2 types
lymphocytes - T&B cells
NK killer cells
neutrophiles granule appearance
none 90-95%
polymorphonucleur cell inflammatory reapose are
neutrophils
monocyte 5-10% short live and will enter extravascular pool become
macrophages as resident in tissue
dendritic cells hv many cytoplamic process as antigen presenting cell found in
peripheral blood, lymph nodes, bone marrow, tissu
lymphoid lineage have high T lymphocyte in
blood circulation
site of production of B lymphocytes (plasma cells0
bone marrow,
spleen (50-60%)
t lymphocytes mature in
thymus
plasma cells or matured b cell produce
antibody
2types of T lymphocytes are
CD4/ helper T cells -regulate other immune cells/antibody
CD8/ cytotoxic T lymphocytes- kill infected cells
natural killer dont need thymus to mature l fx
kill and lyse virus infected cells and tumor cells