Viral infections of skin and soft tissue I Flashcards
In which skin layer are new HPV virions forming?
Suprabasal
HPV belongs to what family?
Papovaviridae
Is HPV enveloped or non-enveloped?
Non-enveloped
What is the HPV genome?
dsDNA
What is the diagnosis for HPV warts?
Hyperkeratosis and koilocytes
What are koilocytes?
Cells with an aberrant, large nucleus surrounded by an unstained halo
What condition is characterized by large eosinophilic cytoplasmic inclusions?
Molluscum contagiosum (molluscum bodies)
Molluscum contagiosum belongs to what family?
Poxviridae
What is the molluscum contagiosum genome?
Large dsDNA
Where does molluscum contagiosum replicate?
Cytoplasm
Is HSV enveloped?
Yes
What is the HSV genome?
dsDNA
What is characteristic about chickenpox lesions?
Found in crops - multiple evolutionary stages in that area of the body
What virus is responsible for chickenpox?
Varicella-zoster virus
What is the cause of shingles?
Varicella-zoster virus reactivation
What family does varicella-zoster virus belong to?
Herpesviridae
Is varicella-zoster virus enveloped or non-enveloped?
Enveloped
What is the varicella-zoster virus genome?
dsDNA
Where does varicella-zoster virus maintain latency?
Trigeminal nerve
How many serotypes of varicella-zoster virus exist?
One
How is varicella-zoster virus diagnosed?
Tzanck smear, ELISA, latex agglutination
What type of vaccine is the varicella vaccine?
Live attenuated
The zoster vaccine is recommended for people of what age group?
Over age 60
