Viral infections of blood and tissues II Flashcards
What are the most common viruses causing myocarditis?
Adenoviruses, enteroviruses
What is the preferred diagnostic method for myocarditis?
PCR
Mumps virus belongs to what family?
Paramyxoviridae
What is the mumps virus genome?
-ssRNA
When is MMRV vaccine initiated?
1st dose 12-15 months, 2nd dose 4-6 years
Kaposi’s sarcoma has what cellular morphology?
Spindle
Is HHV8 enveloped?
Yes
What is the HHV8 genome?
dsDNA
What is the presentation for adult T cell lymphoma?
Lymphadenopathy, hepatosplenomegaly, hypercalcemia, skin infiltration of tumor cells
What is the key cytological marker of adult T cell lymphoma?
Flower cells
What is the diagnosis for adult T cell lymphoma?
Detection of antibodies to human T cell leukemia virus 1 (HTLV-1)
What are the symptoms of HTLV-1 associated myelopathy (HAM)?
Stiff gait, lower extremity weakness, back pain, incontinence
Does human T cell leukemia virus have an envelope?
Yes
What is the human T cell leukemia genome?
+ssRNA
What is one main difference between HTLV and HIV infection?
HTLV targets the GLUT-1 receptor for entry