VIH Flashcards

1
Q

Prueba diagnostica primera elección

A

VIH

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2
Q

Estudio confirmatorio VIH

A

Western BLOT

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3
Q

cuando iniciar terapia antiretroviral

A

independientemente del conteo de CD4

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4
Q

Profilaxis primaria Pneumocysticis jirovecii

A

Uso de dosis altas inmunosupresores y recuento CD4 < 250 celulas en contexto de VIH negativo

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5
Q

Farmaco eleccion profilaxis P. jiroveci

A

TMP SMX

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6
Q

Profilaxis toxoplasma gondii

A

Linfocitos TCD4 <100 celulas y anticuerpos IgG + antitoxoplasma

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7
Q

Farmaco eleccion profilaxis primaria Toxoplasma gondii

A

TMP SMX

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8
Q

Esquemas antiretrovirales

A

TENOFOVIR/ EMTRICITABINA + EFAVIRENZ

ABACAVIR/ LAMIVUDINA + DOLUTEGRAVIR

TENOFOVIR/EMCITRABINA + DOLUTEGRAVIR

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9
Q

Inhibidor de la transcriptasa inversa analogo de nucleosidos y nucleotidos

A

Tenofovir

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10
Q

Antiretrovirales que se asocia a pancreatitis aguda

A

Didanosina

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11
Q

Qué individuos tienen alto riesgo para adquirir Criptococcosis

A
VIH con TCD4<100
Cancer hematologico
receptores de trasplantes de organos solidos
Tx inmunodepresor continuo
Tx largo glucocorticoides
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12
Q

Que especies pueden causas criptococosis

A

C neoformans y C gatti

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13
Q

Donde se adquiere criptococcosis

A

exposicion a suelos contaminados por excretas de aves o palomas, tierras poco iluminadas y humedas

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14
Q

A partir de cuantos T CD4 hay mas riesgo de criptococcosis

A

<100

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15
Q

Dx criptococcosis

A

Tinta china
cultivo
Microscopia de LCR
Deteccion de antigeno

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16
Q

caracteristicas LCR criptococcosis

A

Pleocitosis a expensas de mononucleares e hiperproteinorraquia

17
Q

Tincion mas util para diagnostico rapido criptococosis

A

Demostracion de levaduras en tejidos con tincion de tinta china

18
Q

Tx eleccion criptococosis

A

Anfotericina B + flucitosina 2 semanas, seguido de fluconazol 10 semanas y mas tardde tx de mantenimiento 1 año con fluconazol.

19
Q

Mecanismo de accion imidazoles

A

Inhibicion de 14 a esterol desmetilasa, altera la sintesis de ergosterol de la membrana citoplasmatica

20
Q

Factor pronostico criptococcosis

A

La extension y duracion de la deficiencia inmunitaria subyacente predispone a desarrollar la enfermedad.