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Drug Of The Day > Verapamil > Flashcards

Verapamil Flashcards

1
Q

What is the class of drug of verapamil?

A

Non dihydropyridine CCBs - phenylalkamine
Class IV antiarrhythmic

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2
Q

What are the uses of verapamil?

A

Supraventricular arrhythmias
Angina
Cluster headaches
Hypertension

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3
Q

What is the mechanism of action verapamil?

A

calcium channel blocker
- blocks L type calcium channels > slows Ca2+ influx > prolongs plateau (refractory) phase in myocytes
- in SA nose prolongs depolarisation by blocking L type Ca2+ channels

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4
Q

What are the adverse effects of verapamil?

A

Bradycardia
Heart block
Constipation
Headaches + dizziness

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5
Q

What are the important drug drug interactions of verapamil?

A
  • Beta blockers - slows heart rate to much + increases risk of heart block
  • Other antihypertensives or antiarrhythmics
  • Statins - increases [plasma]
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Drug Of The Day (26 decks)

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