Apixaban Flashcards
1
Q
What is the class of drug of Apixaban?
A
DOACs
2
Q
Uses of Apixaban
A
- PE
- DVT
- AF
3
Q
What is the mechanism of action of Apixaban
A
Inhibits both free Xa + bound to ATIII
4
Q
What are the adverse drug reactions of DOACs?
A
Bleeding
Skin reactions
Anaemia
Nausea
5
Q
What are important drug drug interactions with Apixaban?
A
- carbamazepine, phenytoin + barbiturates decrease [plasma]
- macrolides increase [plasma]
