Fentanyl Flashcards
1
Q
What class of drug is fentanyl?
A
Therapeutic opioid
2
Q
What are the uses of fentanyl?
A
- analgesia
- antitussive (cough suppression)
- dyspnoea
- anaesthetic
- anti-diarrhoea
- palliation
3
Q
What is the mechanism of action of fentanyl?
What is the onset of + duration of action?
What are the methods of administration?
A
- Strong opioid receptor agonist for u receptor
- Fast onset + short duration of action
- Inhaled, IV, epidural, intra thecal
4
Q
What are the adverse drug reactions of fentanyl?
A
- Constipation + urinary retention
- Drowsiness
- dysphoria + euphoria
- hyperhydrosis
- respiratory depression
- nausea
- itching
5
Q
What are the important drug drug interactions of fentanyl?
A
- CNS depressants e.g. anti-epileptic drugs, benzodiazepines
- other opioid containing drugs
- drugs that can reduce gut motility
