Vasopressin

Question 1

What is the correct concentration of Vasopressin when a 20-unit vial is diluted in 19 mL of normal saline (NS)?

A) 0.5 units/mL
B) 1 unit/mL
C) 2 units/mL
D) 5 units/mL

Answer 1

B) 1 unit/mL
Dilute a 20u vial in 19mLNS=1u/mL

Question 2

What is the gtt Dose and dilution of Vasopressin?

Answer 2

0.01-0.1 u/min

Question 3

What is the onset time of action for Vasopressin when administered intravenously?

A) 10-15 minutes
B) 5-10 minutes
C) 1-2 minutes
D) 30-60 seconds

Answer 3

C) 1-2 minutes

Question 4

What is the typical duration of action (DOA) for Vasopressin when used in vasodilatory shock?

A) 5-10 minutes
B) 10-20 minutes
C) 30-60 minutes
D) 1-2 hours

Answer 4

B) 10-20 minutes

Question 5

Which statement best describes the combined effects of V1 and V2 receptor activation by Vasopressin?

A) V1 receptor activation decreases heart rate, and V2 receptor activation increases urine output.
B) V1 receptor activation causes vasodilation, while V2 receptor activation decreases blood pressure.
C) V1 receptor activation leads to peripheral vasoconstriction and increased SVR, while V2 receptor activation facilitates water reabsorption and plasma volume expansion.
D) V1 and V2 receptor activation both result in vasodilation and decreased systemic vascular resistance.

Answer 5

C) V1 receptor activation leads to peripheral vasoconstriction and increased SVR, while V2 receptor activation facilitates water reabsorption and plasma volume expansion.

Question 6

Why should Vasopressin be used with caution in patients with pulmonary hypertension?

A) It decreases pulmonary vascular resistance
B) It increases pulmonary artery pressures
C) It causes pulmonary vasodilation
D) It decreases cardiac output

Answer 6

B) It increases pulmonary artery pressures

CAUTION: Vasopressin may ↑PA pressures as well as induce coronary vasoconstriction.

Question 7

Why might Vasopressin be useful in patients with mitral stenosis?

A) It increases cardiac output
B) It causes peripheral vasoconstriction, which helps maintain systemic blood pressure
C) It increases pulmonary blood flow
D) It decreases heart rate, improving diastolic filling

Answer 7

B) It causes peripheral vasoconstriction, which helps maintain systemic blood pressure