Dobutamine - Beta Adrenergic Agonist

Question 1

What is the typical dosing range for Dobutamine when used as an infusion?

A) 1-5 mcg/min
B) 5-15 mcg/min
C) 20-50 mcg/min
D) 50-100 mcg/min

Answer 1

Answer: B) 5-15 mcg/min

Question 2

What is the concentration of Dobutamine in a standard preparation?

A) 1 mg/mL
B) 5 mg/mL
C) 10 mg/mL
D) 50 mg/mL

Answer 2

A) 1 mg/mL
(250 mg/250mL)

Question 3

What is the duration of action (DOA) of Dobutamine?

A) 1-2 minutes
B) 2-5 minutes
C) 5-10 minutes
D) 10-15 minutes

Answer 3

A) 1-2 minutes

Question 4

Which effects of Dobutamine contribute to the reduction of afterload?

A) Increased contractility and heart rate
B) Peripheral vasoconstriction and reduced coronary blood flow
C) Dilation of skin and skeletal muscle vascular beds
D) Increased systemic vascular resistance (SVR)

Answer 4

C) Dilation of skin and skeletal muscle vascular beds

Question 5

Which of the following best describes the mechanism of action (MOA) of Dobutamine?

A) Beta-2 agonist that dilates peripheral vessels and increases heart rate
B) Beta-1 agonist that increases myocardial contractility and cardiac output
C) Alpha-1 antagonist that reduces peripheral vasoconstriction
D) Beta-1 antagonist that decreases heart rate and myocardial contractility

Answer 5

Answer: B) Beta-1 agonist that increases myocardial contractility and cardiac output

MOA: Positive inotrope. Beta 1 agonist. Coronary Increases contractility & CO, sime increases in HR, and peripheral vasoconstriction.

Question 6

Why is Dobutamine particularly useful when coming off the pump in cardiac surgery?

A) It decreases heart rate and myocardial contractility.
B) It increases cardiac output (CO) and cardiac index (CI) by enhancing myocardial contractility.
C) It lowers blood pressure significantly.
D) It causes vasoconstriction and increases systemic vascular resistance (SVR).

Answer 6

Answer: B) It increases cardiac output (CO) and cardiac index (CI) by enhancing myocardial contractility.

Question 6

Which of the following conditions is Dobutamine commonly used to manage in the context of anesthesia?

A) Hypertension
B) Cardiogenic shock
C) Hypovolemic shock
D) Acute renal failure

Answer 6

B) Cardiogenic shock

Question 7

In which clinical scenario would Dobutamine be particularly beneficial to administer?

A) Patients with refractory congestive heart failure (CHF)
B) Patients with severe hypovolemic shock
C) Patients with uncontrolled hypertension
D) Patients with acute respiratory distress syndrome (ARDS)

Answer 7

A) Patients with refractory congestive heart failure (CHF)

Question 8

When administering Dobutamine, which of the following parameters are likely to increase?
(Select 3)

A) Blood Pressure (BP)
B) Heart Rate (HR)
C) Cardiac Output (CO) / Cardiac Index (CI) and CVP
D) Systemic Vascular Resistance (SVR)

Answer 8

B) Heart Rate (HR)
C) Cardiac Output (CO) / Cardiac Index (CI) and CVP

Question 9

What effect does Dobutamine have on systemic vascular resistance (SVR)?

A) Increases SVR significantly
B) Decreases SVR due to peripheral vasodilation
C) Has no effect on SVR
D) Increases SVR slightly due to alpha-agonism

Answer 9

B) Decreases SVR due to peripheral vasodilation

(still has slight alpha agonism however)

Question 10

Which of the following is a known effect of Dobutamine on pulmonary?

A) Enhances hypoxic pulmonary vasoconstriction
B) Inhibits hypoxic pulmonary vasoconstriction
C) Has no effect on pulmonary vasoconstriction
D) Induces hypoxic pulmonary vasoconstriction

Answer 10

B) Inhibits hypoxic pulmonary vasoconstriction