Aminocaproic Acid (Amicar) - Antifibrinolytic

Question 1

What is the typical dosing range for Aminocaproic Acid (Amicar)?
Select all that apply.

A) 50-100 mg/kg over 6 hours
B) 50-100 mg/kg every 2 hours
C) 10-20 mg/kg over 24 hours
D) 50-100 mg/kg over 12 hours

Answer 1

A) 50-100 mg/kg over 6 hours

Question 2

What is the primary mechanism of action (MOA) of Aminocaproic Acid (Amicar)?

A) Inhibits the activation of plasminogen to plasmin
B) Enhances the degradation of fibrin clots
C) Decreases bleeding time by preventing plasminogen activation
D) Promotes clot formation by activating fibrinogen

Answer 2

A) Inhibits the activation of plasminogen to plasmin

MOA: Inhibits activation of plasminogen to plasmin, an enzyme that degrades fibrin clots. (↓bleed time)

Question 3

How does Aminocaproic Acid (Amicar) help in controlling bleeding?
Select 2.

A) By inhibiting the conversion of plasminogen to plasmin
B) By promoting the breakdown of fibrin clots
C) By decreasing the enzymatic degradation of fibrin
D) By enhancing the activation of plasminogen
D) By enhancing the activation of plasminogen

Answer 3

A) By inhibiting the conversion of plasminogen to plasmin

C) By decreasing the enzymatic degradation of fibrin