Esmolol Flashcards
What is the concentration of Esmolol in a 10 cc vial?
A) 5 mg/mL
B) 10 mg/mL
C) 20 mg/mL
D) 50 mg/mL
B) 10 mg/mL
What is the IVP Dose & Dilution of Esmolol?
10-20 mg
Have ready but not drawn up – 10cc vial = 10mg per mL
What is the recommended loading dose of Esmolol for intravenous administration?
A) 0.1 mg/kg
B) 0.25 mg/kg
C) 0.5 mg/kg
D) 1 mg/kg
C) 0.5 mg/kg
What is the range of infusion rates for Esmolol?
A) 10-50 mcg/kg/min
B) 25-100 mcg/kg/min
C) 50-300 mcg/kg/min
D) 100-500 mcg/kg/min
C) 50-300 mcg/kg/min
(2500mg in 250 mL = 10mg/mL)
What is the onset time of Esmolol when administered intravenously?
A) 30 seconds
B) 1-2 minutes
C) 5 minutes
D) 10 minutes
B) 1-2 minutes
What is the peak effect time for Esmolol after intravenous administration?
A) 1 minute
B) 3 minutes
C) 5 minutes
D) 10 minutes
C) 5 minutes
How long does the effect of Esmolol typically last?
A) 1-5 minutes
B) 5-15 minutes
C) 30 minutes
D) 1-2 hours
B) 5-15 minutes
What is the mechanism of action (MOA) of Esmolol?
A) Non-selective Beta blocker
B) Selective Beta-2 antagonist
C) Short-acting selective Beta-1 antagonist
D) Alpha-1 antagonist
C) Short-acting selective Beta-1 antagonist
Why can beta blockade be particularly dangerous in the setting of acute cocaine overdose?
A) It increases the risk of coronary vasospasm
B) It decreases the effectiveness of vasodilators
C) It enhances catecholamine release
D) It prolongs the duration of cocaine action
A) It increases the risk of coronary vasospasm
How is Esmolol metabolized in the body?
A) Hepatic oxidation
B) Ester hydrolysis
C) Renal excretion
D) Glucuronidation
Answer: B) Ester hydrolysis
What is a potential consequence of administering beta-blocking drugs in the presence of catecholamine-induced hypertension and tachycardia?
A) Enhanced vasodilation
B) Profound cardiovascular collapse
C) Increased catecholamine levels
D) Decreased blood pressure
B) Profound cardiovascular collapse
