Antithrombin III

Question 1

In which situation is Antithrombin III (ATIII) commonly used during cardiovascular (CV) surgery?
Select 2

A) If two doses of heparin are inadequate
B) In the case of severe hemorrhage
C) When there is a rare event of ATIII deficiency
D) When heparin is contraindicated due to allergies

Answer 1

A) If two doses of heparin are inadequate

C) When there is a rare event of ATIII deficiency

Question 2

What is the underlying cause of thrombosis in patients with Antithrombin III (ATIII) deficiency?
Select 2

A) Thrombosis can be induced by stimuli that do not usually lead to thrombus formation
B) Thrombosis occurs only during high-dose heparin therapy
C) Deficiency of ATIII leads to an inability to inhibit clotting factors like thrombin
D) Excessive bleeding during surgery

Answer 2

A) Thrombosis can be induced by stimuli that do not usually lead to thrombus formation

C) Deficiency of ATIII leads to an inability to inhibit clotting factors like thrombin

Question 3

Why might Antithrombin III (ATIII) be administered in cases where heparin doses are inadequate?
Select 2

A) To provide an additional anticoagulant effect when heparin is insufficient
B) To increase platelet aggregation
C) To enhance the effect of fibrinogen in clot formation
D) To inhibit thrombin and other clotting factors

Answer 3

A) To provide an additional anticoagulant effect when heparin is insufficient

D) To inhibit thrombin and other clotting factors

Question 4

What is the role of Antithrombin III (ATIII) in the body?
Select 3

A) It inhibits thrombin and other clotting factors
B) It directly promotes clot formation
C) It helps regulate the coagulation cascade
D) It acts as a natural anticoagulant

Answer 4

A) It inhibits thrombin and other clotting factors

C) It helps regulate the coagulation cascade

D) It acts as a natural anticoagulant