VASCULAR DISORDERS

Question 1

A.k.a OSLER WEBER RENDU DISEASE

Answer 1

Hereditary hemorrhagic telangiectasia

Question 2

Gene mutation in Hereditary hemorrhagic telangiectasia

Answer 2

Autosomal dominant

Question 3

Juvenile type in Hereditary hemorrhagic telangiectasia

Answer 3

SMAD4

Question 4

Type III IN Hereditary hemorrhagic telangiectasia

Answer 4

Unknown

Question 5

Type II in Hereditary hemorrhagic telangiectasia

Answer 5

ACVRL

Question 6

Type I Hereditary hemorrhagic telangiectasia

Answer 6

ENG

Question 7

Other name for congenital hemangiomata

Answer 7

Kasabach-Merrit Syndrome
Hemangioma thrombocytopenia syndrome

Question 8

Transcribe DIC

Answer 8

Disseminated intravascular coagulation

Question 9

Indicative of DIC

Answer 9

Congenital hemangiomata

Question 10

Vascular disorder common to newborn

Answer 10

Congenital hemangiomata

Question 11

Immunoglobulin deposit in the cutaneous BV resulting to fragility, purpuraa d trauma

Answer 11

Multiple myeloma

Question 12

Due to abnormal production of L chain by plasma cells in the BM

Answer 12

Systemic amyloidosis

Question 13

Characterized by insoluble amyloid filament attached to a polysaccharide

Answer 13

Systemic amyloidosis

Question 14

Causes cerebral infarcts in children and intracranial hemorrhage in adult

Answer 14

Moyamoya disease

Question 15

Blockage of arteries

Answer 15

Moyamoya disease

Question 16

Results to fragile arterioles causing recurrent ischemic strokes and cognitive impairement

Answer 16

Cerebral small vessel disease

Question 17

Causes narrowing and weakening of BV

Answer 17

Vasculitis

Question 18

Causes narrowing and weakening of BV

Answer 18

Vasculitis

Question 19

Seen in SLE and wegener’s granulomatosis

Answer 19

Antineutrophilic cytoplasmic antibody-positive

Question 20

Transcribe ANCA

Answer 20

Antineutrophilic cytoplasmic antibody-positive

Question 21

Targets the primary granules of neutrophils

Answer 21

Antineutrophilic cytoplasmic antibody-positive

Question 22

What cANCA targets

Answer 22

Proteinase 3

Question 23

What does pANCA targets

Answer 23

Myeloperoxidase

Question 24

Associated with cryoglobulin deposits

Answer 24

Cryoglobulinemia

Question 25

Characteristic of blood in cryoglobulinemia

Answer 25

Hyper viscous

Question 26

Cryoglobulin precipitates at what temperature

Answer 26

Cold temperature

Question 27

What factor is low in cryoglobulinemia

Answer 27

FXIII

Question 28

Seen in waldenstrom's primary macroglobulinemia

Answer 28

Cryoglobulinemia

Question 29

What are the infected associated prupura

Answer 29

1. Rickettsial disease 2. Brazillian purpura fever 3. Rat Bite fever 4. Vibrio vulniricans infection 5. Strongyloides 6. Acquired purpura fulminans

Question 30

Occurs to women during menstrual cycle

Answer 30

Purpura simplex

Question 31

Miscellaneous causes of purpura can be a result of

Answer 31

1. Contact dermatitis 2. Steroid use 3. Drug reaction 4. Allergies

Question 32

Observed in miscellaneous causes of purpura

Answer 32

1. Kaposi sarcoma 2. Vascular tumor

Question 33

Observed in miscellaneous causes of purpura

Answer 33

1. Kaposi sarcoma 2. Vascular tumor