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HEMATOLOGY 2 SUMMER TERM > VASCULAR DISORDERS > Flashcards

VASCULAR DISORDERS Flashcards

1
Q

A.k.a OSLER WEBER RENDU DISEASE

A

Hereditary hemorrhagic telangiectasia

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2
Q

Gene mutation in Hereditary hemorrhagic telangiectasia

A

Autosomal dominant

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3
Q

Juvenile type in Hereditary hemorrhagic telangiectasia

A

SMAD4

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4
Q

Type III IN Hereditary hemorrhagic telangiectasia

A

Unknown

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5
Q

Type II in Hereditary hemorrhagic telangiectasia

A

ACVRL

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6
Q

Type I Hereditary hemorrhagic telangiectasia

A

ENG

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7
Q

Other name for congenital hemangiomata

A

Kasabach-Merrit Syndrome
Hemangioma thrombocytopenia syndrome

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8
Q

Transcribe DIC

A

Disseminated intravascular coagulation

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9
Q

Indicative of DIC

A

Congenital hemangiomata

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10
Q

Vascular disorder common to newborn

A

Congenital hemangiomata

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11
Q

Immunoglobulin deposit in the cutaneous BV resulting to fragility, purpuraa d trauma

A

Multiple myeloma

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12
Q

Due to abnormal production of L chain by plasma cells in the BM

A

Systemic amyloidosis

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13
Q

Characterized by insoluble amyloid filament attached to a polysaccharide

A

Systemic amyloidosis

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14
Q

Causes cerebral infarcts in children and intracranial hemorrhage in adult

A

Moyamoya disease

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15
Q

Blockage of arteries

A

Moyamoya disease

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16
Q

Results to fragile arterioles causing recurrent ischemic strokes and cognitive impairement

A

Cerebral small vessel disease

17
Q

Causes narrowing and weakening of BV

A

Vasculitis

18
Q

Causes narrowing and weakening of BV

A

Vasculitis

19
Q

Seen in SLE and wegener’s granulomatosis

A

Antineutrophilic cytoplasmic antibody-positive

20
Q

Transcribe ANCA

A

Antineutrophilic cytoplasmic antibody-positive

21
Q

Targets the primary granules of neutrophils

A

Antineutrophilic cytoplasmic antibody-positive

22
Q

What cANCA targets

A

Proteinase 3

23
Q

What does pANCA targets

A

Myeloperoxidase

24
Q

Associated with cryoglobulin deposits

A

Cryoglobulinemia

25
Q

Characteristic of blood in cryoglobulinemia

A

Hyper viscous

26
Q

Cryoglobulin precipitates at what temperature

A

Cold temperature

27
Q

What factor is low in cryoglobulinemia

A

FXIII

28
Q

Seen in waldenstrom’s primary macroglobulinemia

A

Cryoglobulinemia

29
Q

What are the infected associated prupura

A
  1. Rickettsial disease
  2. Brazillian purpura fever
  3. Rat Bite fever
  4. Vibrio vulniricans infection
  5. Strongyloides
  6. Acquired purpura fulminans
30
Q

Occurs to women during menstrual cycle

A

Purpura simplex

31
Q

Miscellaneous causes of purpura can be a result of

A
  1. Contact dermatitis
  2. Steroid use
  3. Drug reaction
  4. Allergies
32
Q

Observed in miscellaneous causes of purpura

A
  1. Kaposi sarcoma
  2. Vascular tumor
33
Q

Observed in miscellaneous causes of purpura

A
  1. Kaposi sarcoma
  2. Vascular tumor

HEMATOLOGY 2 SUMMER TERM (16 decks)

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