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HEMATOLOGY 2 SUMMER TERM > PLATELET LEC > Flashcards

PLATELET LEC Flashcards

1
Q

small packages of cytoplasm that are nipped off from the cytoplasm of megakaryocytes

A

PLATELETS

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2
Q

nipped off from the cytoplasm of megakaryocytes through the process known as

A

THROMBOPOIESIS

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3
Q

Platelet is considered as true cell.
TRUE OR FALSE

A

FALSE

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4
Q

precursor of platelet

A

MEGAKARYOCYTE

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5
Q

4 STAGES OF MEGAKARYOPOIESIS

A

1.Megakaryoblast
2.Promegakaryocyte
3. Megakaryocyte
4. Metamegakaryocyte

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6
Q

Metamegakaryocyte

A

FUTURE PLATELET

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7
Q

resembles myeloblast and pronormoblast

A

MEGAKARYOBLAST

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8
Q

Cytoplasm is abundant, minimal lobularity

A

PROMEGAKARYOCYTE

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9
Q

most immature stage

A

MEGAKARYOBLAST

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10
Q

Nucleus is lobulated and basophilic

A

MEGAKARYOCYTE

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11
Q

Cytoplasm is granular and azurophilic with DMS

A

MEGAKARYOCYTE

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12
Q

extension of cytoplasm

A

DMS

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13
Q

COLOR PRESENT IN MEGAKARYOCYTE

A

DARK BLUE DEMARCATION

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14
Q

HORMONE INVOLED IN PLT

A

THROMBOPOIETIN

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15
Q

Nucleus of MKI

A

Round

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16
Q

Nucleus of MKII

A

Indented

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17
Q

Nucleus of MKIII

A

Multilobed

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18
Q

Chromatin of MKI

A

Homogenous

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19
Q

Chromatin of MKII

A

Moderately condensed

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20
Q

Chromatin of MKIII

A

Deeply and variably condensed

21
Q

Endomitosis of MKI

A

Present

22
Q

Endomitosis of MKII

A

Ends

23
Q

Endomitosis of MKIII

A

Absent

24
Q

SIZE of plt:

A

2-4 um

25
Q

MPV:

A

7fL

26
Q

Lifespan:

A

9-10 days

27
Q

Normal count

A

150-450X10^9/L

28
Q

Type of Platelet

A

a. resting platelet
b. stress platelet

29
Q

resting platelet

A

(circulatin g platelet)

30
Q

stress platelet

A

(reticulated platelet)

31
Q

Size and shape of resting plt

A

Normally biconvex

32
Q

Markedly larger than normal platelet >6 um

A

Stress platelet

33
Q

MPV of stress plt

A

12-14 fL

34
Q

Citrated blood: cylindrical

A

Stress plt

35
Q

Wright stained smear: circular/ irregular

A

Resting plt

36
Q

Carry ribosomes and fragments of RER

A

Stress plt

37
Q

Flow smoothly in vein

A

Resting plt

38
Q

direct communication with extracellular environment

A

Open canalicular system

39
Q

site of arachidonic acid synthesis

A

Dense tubular system

40
Q

platelet fibrinogen

A

PF 5

41
Q

anti-heparin factor

A

PF 4

42
Q

lipoprotein

A

PF 3

43
Q

Inhibits antithrombin II

A

PF 2

44
Q

Plasma coagulation factor V

A

PF 1

45
Q

adheres to detached/injured
endothelium

A

Adhesion

46
Q

platelet release reaction

A

-alpha and dense granules release substance
-shape change

47
Q

glycoprotein and fibrinogen

A

Plt agreggation

48
Q

serotonin

A

Vasoconstriction

49
Q

clot formation:

A

PF3

HEMATOLOGY 2 SUMMER TERM (16 decks)

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