PLATELET LEC Flashcards

1
Q

small packages of cytoplasm that are nipped off from the cytoplasm of megakaryocytes

A

PLATELETS

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2
Q

nipped off from the cytoplasm of megakaryocytes through the process known as

A

THROMBOPOIESIS

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3
Q

Platelet is considered as true cell.
TRUE OR FALSE

A

FALSE

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4
Q

precursor of platelet

A

MEGAKARYOCYTE

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5
Q

4 STAGES OF MEGAKARYOPOIESIS

A

1.Megakaryoblast
2.Promegakaryocyte
3. Megakaryocyte
4. Metamegakaryocyte

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6
Q

Metamegakaryocyte

A

FUTURE PLATELET

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7
Q

resembles myeloblast and pronormoblast

A

MEGAKARYOBLAST

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8
Q

Cytoplasm is abundant, minimal lobularity

A

PROMEGAKARYOCYTE

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9
Q

most immature stage

A

MEGAKARYOBLAST

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10
Q

Nucleus is lobulated and basophilic

A

MEGAKARYOCYTE

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11
Q

Cytoplasm is granular and azurophilic with DMS

A

MEGAKARYOCYTE

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12
Q

extension of cytoplasm

A

DMS

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13
Q

COLOR PRESENT IN MEGAKARYOCYTE

A

DARK BLUE DEMARCATION

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14
Q

HORMONE INVOLED IN PLT

A

THROMBOPOIETIN

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15
Q

Nucleus of MKI

A

Round

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16
Q

Nucleus of MKII

A

Indented

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17
Q

Nucleus of MKIII

A

Multilobed

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18
Q

Chromatin of MKI

A

Homogenous

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19
Q

Chromatin of MKII

A

Moderately condensed

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20
Q

Chromatin of MKIII

A

Deeply and variably condensed

21
Q

Endomitosis of MKI

22
Q

Endomitosis of MKII

23
Q

Endomitosis of MKIII

24
Q

SIZE of plt:

25
MPV:
7fL
26
Lifespan:
9-10 days
27
Normal count
150-450X10^9/L
28
Type of Platelet
a. resting platelet b. stress platelet
29
resting platelet
(circulatin g platelet)
30
stress platelet
(reticulated platelet)
31
Size and shape of resting plt
Normally biconvex
32
Markedly larger than normal platelet >6 um
Stress platelet
33
MPV of stress plt
12-14 fL
34
Citrated blood: cylindrical
Stress plt
35
Wright stained smear: circular/ irregular
Resting plt
36
Carry ribosomes and fragments of RER
Stress plt
37
Flow smoothly in vein
Resting plt
38
direct communication with extracellular environment
Open canalicular system
39
site of arachidonic acid synthesis
Dense tubular system
40
platelet fibrinogen
PF 5
41
anti-heparin factor
PF 4
42
lipoprotein
PF 3
43
Inhibits antithrombin II
PF 2
44
Plasma coagulation factor V
PF 1
45
adheres to detached/injured endothelium
Adhesion
46
platelet release reaction
-alpha and dense granules release substance -shape change
47
glycoprotein and fibrinogen
Plt agreggation
48
serotonin
Vasoconstriction
49
clot formation:
PF3