vascular disease pathophys Flashcards
examples of obstructive arterial disease
atherosclerosis, vasospasm, arterial fibrosis, inflam, embolism
atherosclerosis
plaque formation, turbulent/non laminar flow
clin synptoms depend on
location
tests for atherosclerosis
function (stress/ABI), anatomic (angiogram)
treat atherosc
statins and aspirin and stent/bypass
natural solutions to atherosclerosis
collateral arteries, dilation distal arteriole, decreased tissue metabolism, increased o2 excretion
thrombus path
limid MP> oxidation, cell proliferation
risk factors for thrombus
Abel lipid, Dm, HTN, smoke
targets for treatment
LDL cholesterol, triglycerides, platelet inhib
why to platelet inhibitors work?
asprin blocks thromboxane, which increases platelet aggregation/thrombosis