cardiac electrophysiology Flashcards
types of cardiac cells
pacemaker or non
pacemaker cell info
specialized myocardial cells, in SA/AV nodes,/ his/perk.. Dif patterns, auto rhythmic
3 sections of pacemaker AP
phase 4 depol, depol, repol
phase 4 depol
pacemaker potential. slow rise to threshold, decreased K efflux, if current, gradual ca influx= net positive
if current
slow Na influx (non spec/leaky
depol pacemaker
voltage gated ca2+ efflux (dom inward current)
repol pacemaker
volt gated K+ efflux
nervous control of pacemaker parasympha:
ACH to av node, decrease If, decrease ca in phase 4
nervous control of pacemaker sympha:
cardiac plexus, norepinephrine, increase If/ca in phase 4, decrease threshold to more neg
non pacemaker cell info
not autorhythmic, 5 phase
stages non pacemaker Ap
0: Na influx/voltage gated. 1: inactivate na, 2: plate, open ca in, close K out, 3: ca2+ channels close, k efflux, 4: resting pot (small k/ na)
refractory absolute for non pacemaker
0-part of 3, na channel are inactive. allows time for heart to refill ( no tetany)
conduction of AP between cells
gap junctions, low R ion channel, spread of depol,