path of CAD Flashcards

1
Q

main cardiac cause of death in USA

A

80% coronary ischemic heart disease. also congee, valve, HTN

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2
Q

clin of CAD

A

angina pectoris, MI, chronic ischemic, sudden death

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3
Q

types of angina pectoris

A

chronic stable, prinz, unstable crescendo

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4
Q

risk factors for CAD

A

smoking, HTN, smoking, age, SM, obesity, FH, sex

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5
Q

path of MI

A

acute plaque change> block vessel

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6
Q

types of infarction

A

transmural, subendocardial, multifocal

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7
Q

transmural

A

entire wall (endo>episode), most common, usually LAD, right, or Lcx

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8
Q

subendocardial

A

inner 1/3 have LU, usually circumflex, mult vessels. hypoerfusion, shock

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9
Q

micro changes 24 hours

A

wavy fibers, contraction nabs necrosis, eosinophilic myocyes,

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10
Q

24 hr macro

A

cut surface pallor, dark motility

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11
Q

2-4 day micro

A

PNMs, interstitial edema/hemm, no nuclei, loose striation

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12
Q

2-4 day macro

A

rotting with yellow/tan

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13
Q

7-10 day micro

A

few PNM, Mphage, fblast/collogen, lymphcoytes

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14
Q

7-10 macro

A

sharp hyperemic outline, central necrotic region (pale, gelat)

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15
Q

2-8 week micro

A

granulation tissue, blast, chronic inflam

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16
Q

2-8 week macro

A

gret/white scar. aneurysm risk

17
Q

complications of MI

A

contractile disfunction (shock), arrhythmia, rupture, aneurysm, mural thromb/embolism