path of valvular heart disease Flashcards
normal valves
thin, delicate, smooth, mobile, pliable,
normal valve histo
fibrosa, spongiosa, atrialis, ventriculares (A/V are elastci)
rheumatic fever
acute, immune mediated, inflammatory, multisystemic
path
heart, joints, skin, brain. group A strep. antibodies> glucoproteins
diag for rheum
2 major jones, 1 major two minor
histo rheum
Aschoff nodule, firanoid necrosis, hystictye (giant cell)
antiskow cells
catipliawr, Mphage
complications from RF
endocarditis (acute), ends carditis (chronic) mitral stenosis (fish mouth)
acute endocardidits
normal valve, virulent org, damage high, high mortality
subacute endocarditis
less mortality because time to compensate .. less pathologic organism
organisms for endocarditis
alpha hemolytic strap, staph aures (virulent)
endocarditis path
bulky, grille vitiations, everywhere
calcification
aging, bicuspid increases, increase LV pressure, concentric hypertrophy (ischemia), chest pain, HF, syncope
mitral prolapse
floppy, redundant, ballon tissue, think, can’t seal
myozomatous degentration
mitral prolapse