pharm of angina

Question 1

nitrates MOA

Answer 1

increased CGMP… vasoactivate» ventilation, increase coronary flow short term

Question 2

net effect of nitrates

Answer 2

decreased MO2 demand (decrease afterload/preload)

Question 3

side effects of nitrates

Answer 3

increase tachycardia/inotroped

Question 4

nitrate interaction

Answer 4

sildenafil, increase cGMP levels, combo leads to massive dilation

Question 5

beta blocker net effect

Answer 5

decrease MO2 demand, decrease HR, BP, contractility,

Question 6

anti anginal BP effects

Answer 6

increase exercisee toll, decrease HR at rest and exercise, SNAs contention

Question 7

Non Dih CCB

Answer 7

myocardial effect, vasodilatie, electro effect (increase conduction time, decrease HR) (AV block)

Question 8

Dihydropine CCB

Answer 8

increased effect on vascular SM tone, tissue selective, no electro (ambled)

Question 9

net effect of CCB

Answer 9

decrease HR (Non), BP, contract

Question 10

what drugs decrease HR

Answer 10

non di CCB, BB,

Question 11

treatment for variant antina

Answer 11

nitrate, CBB

Question 12

combo therapys

Answer 12

long nitro and BB, BB and dished CCB

Question 13

DONT USE THESE COMBOS

Answer 13

BB and no dishy, long act nitrates and dishy CCB