UWorld 12/9/14 Flashcards
What is the clinical presentation of Kallman’s syndrome?
hypogonadotropic hypogonadism and anosmia
What is the pathologic basis of Kallman’s syndrome?
failure of GnRH-secreting (and olfactory) neurons to migrate into the hypothalamus during embryonic development
Sudden, painless vision loss, pale fundus w/ “cherry red spot”.
CRAO
Painless, subacute vision loss, “blood and thunder” retina (hemorrhages and optic disc edema).
CRVO
Floaters, visual field defect, and flashing lights.
Retinal detachment
What is the most common cause of infantile botulism?
ingestion of environmental dust containing C. botulinum spores
What is the classic presentation of infantile botulism (3 things)?
constipation, cranial nerve palsies, and flaccid paralysis
What is the Tx of choice for infantile botulism?
human-derived botulism immune globulin
What is the Tx of choice for adult (foodborne or wound) botulism?
equine-derived botulinum antitoxin
Hypoperfusion from sepsis: IV fluids to a central venous pressure in the range of _____ mmHg.
8-12
Hypoperfusion from sepsis: Add vasopressors if the MAP is <___.
65
Classic triad of Wernicke’s encephalopathy
Confusion, ataxia, and nystagmus
Which diuretics can cause pancreatitis?
Furosemide, HCTZ
Which IBD drugs can cause pancreatitis?
Sulfasalazine, 5-ASA
Which immunosuppressants can cause pancreatitis?
Azathioprine, L-asparaginase
