Kap dat Hematology

Question 1

What special route of administration of MTX is used for ALL?

Answer 1

intrathecal

Question 2

Which type of leukemia is associated with DIC?

Answer 2

AML M3 (Promyelocytic leukemia)

Question 3

What percentage of blasts do you have in the BMin acute leukemia?

Answer 3

> 30%

Question 4

Aside from chemo, what med must be administered in AML M3?

Answer 4

all-trans-retinoic acid (ATRA)

Question 5

What is the best initial diagnostic test for suspected SVC syndrome?

Answer 5

CT w/ contrast

Question 6

What is the imaging modality of choice for suspected bone mets in malignancies with primarily osteoBLASTIC lestions (e.g. prostate ca.)?

Answer 6

radionuclide bone scan

Question 7

What are the imaging modalities of choice for suspected bone mets in malignancies with primarily ostoLYTIC lesions (e.g. multiple myeloma)?

Answer 7

Plain x-rays or PET scan

Question 8

_______ is the major contributor to bleeding tendency in pts w/ renal dysfunction.

Answer 8

Platelet dysfunction

Question 9

What is the simplest and least toxic Tx for increased bleeding time 2/2 plt dysfunction?

Answer 9

Desmopressin

Question 10

How does desmopressin improve bleeding time?

Answer 10

releases Factor VIII and vWF from endothelium

Question 11

2 most common esophageal cancers

Answer 11

adenocarcinoma & squamous cell carcinoma

Question 12

Which kind of esophageal ca. is more associated with smoking and drinking?

Answer 12

squamous cell carcinoma

Question 13

Which kind of espohageal ca. is more associated w/ GERD/Barrett’s esophagus?

Answer 13

adenocarcinoma

Question 14

In which third(s) of the esophagus is squamous cell carcinoma more likely to occur?

Answer 14

upper 1/3

Question 15

In which third(s) of the esophagus is adenocarcinoma most likely to occur?

Answer 15

bottom and middle 1/3’s