UTI- unrein Flashcards

1
Q

level of bifurcation of upper and lower UTI

A

urethral orifices of bladder

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2
Q

risk facotrs UTI

A

female
spermicides
pregnancy
vaginal atrophy

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3
Q

Sx UTI

A

dysuria, frequency, urgency, strong urine odor, cloudy urine, suprapubic tenderness on PE
absence of vaginal discharge or vaginal pain

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4
Q

underlying risk factors for UTI

A

neurogenic bladder
DM
urinary instrumentation
structural abnormalities like cystocele

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5
Q

when is culture indicated even if suspect simple cystitis

A

pregnancy
antibiotic resistant organisms
multiple drug sensitivities
underlying complicating medical condition

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6
Q

complicated cystitis

A
recurrent in female
ANY male
urethral malformations
strictures or obstructions
neurogenic bladder
immunocompromised
renal disease
pregnancy
DM
catheterization
upper tract disease
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7
Q

presentation pyelonephritis

A

fever and toxic appearance
lloyds sign
elevated WBC with lef tshift

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8
Q

what causes pyelonephritis

A

most common- ascending bacteria from residual urine and reflux
hematogenous or lymphatic spread- endocarditis, osteomyelitis, injeciton drug users

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9
Q

where do you palpate kidney

A

anterior hand, should not be able to palpate kidney in normal individual

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10
Q

do you Tx asymptomatic bacteriuria

A

not usually

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11
Q

indications for Tx asymptomatic bacteriuria

A

pregnancy
urinary outflow obstruction
anticipated urinary instrumentation
when the goal is to prevent upper tract disease

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12
Q

what is urosepsis

A

septic
tachy, fever or low temp
elevated WBC left shfit
rigors

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13
Q

what to order for urosepsis

A

blood and urine cultures and imaging

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14
Q

pathogens in urine normally

A

gram - bacteria

gram + bacteria

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15
Q

what bacteria found in young women

A

staphylococcus saprophyticus

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16
Q

what grows on prosthetic devices

A

staph epidermidis

17
Q

what staph occurs in injection drug users

18
Q

what is sterile pyuria

A

doesn’t grow on regular agar

19
Q

what pathogens are “culture negative”

A
mycobacterium TB
adenovirus
polyomavirus
cytomegalovirus
anaerobes
fungal
interstitial cystitis
20
Q

what will a urine dipstick tell you

A

+ nitrites and leukocyte esterase in for UTI

negative nitrites and leukocyt high negative predictive value!!

21
Q

use of urine cultures in lab eval

A

colony counts

antibiotic sensitivity patterns

22
Q

what imaging is used for lab evals

A

US and CT scan

23
Q

what cells make nitrites? nitrates?

A

nitrites prokaryotic cells

nitrates eukaryotic cells

24
Q

Tx UTI that is bacteriostatic

A

nitrofurantoin

25
bactericidal antibiotics used for UTI
TMP/SMX fluoroquinolone beta-lactam antibiotics
26
side effects fluorquinolones
achilles tendon rupture
27
what antibiotic is variably bacetriostatic vs bactericidal
aminoglycosides
28
how long to Tx for simple cystitis
3 days
29
how long to Tx complicated cystitis/pyelonephritis
10-14
30
common complications aminoglycosides
ototoxicity | nephrotoxicity
31
non-antibiotic prophylaxis
topical estriol replacement cranberry methenamine
32
prevention UTI
post coital voiding | double/triple voiding
33
when to use antibiotic UTI
pregnancy DM recurrent UTIs
34
33 M IV drug user with fever and left flank pain shares needles trades sex for drugs elevated WBC count, endocarditis, splinter hemorrhages and rash on palms HIV negative most likely etiology of his pyelonephritis to be?
staph aureus
35
64 M + HIV on broad beta lactam for pneumonia has burning with urination, urinary frequency and urinary urgency + leukocyte esterase and TNTC WBC no growth on cultures most likely causative organism of his urinary tract infection?
candida