Quad Screen and fetal heart rate Flashcards
Describe the office visit plan for pregnant women
every 4 weeks for first 28 weeks
every 2-3 weeks until 36 weeks
every week after 36 weeks
what is the quad screen
maternal blood screening that looks for 4 specific substances
AFP, hCG, Estriol and Inhibin A
what produces AFP
fetus
what produces hCG
placenta
what produces estriol
fetus and placenta
what produces Inhibin A
placenta and ovaries
how will downs present on quad screen
decreased AFP, estriol
Increased hCG and inhibin A
US of downs may show what
nuchal translucency
how will edwards trisomy 18 present on quad screen
decreased: AFP hCG and estriol
normal inhibin A
signs of trisomy 18
severe mental retardation, rocker bottom feet, micrognathia, low set ears, clenched hands, prominent occiput
lifespan of neonates with trisomy 18
50% die within first week
only 8% live beyond year 1
What is trisomy 13
pataus
patau on US
nuchal translucency
trisomy 13 on quad screen
sometimes hCG dec
survival baby with patau
2.5 days
5% make it a year
quad screen recommended especially for women who
\+FMH birth defects 35+ y.o use of harmful medications or drugs during pregnancy DM and use insulin viral infection during pregnancy exposed to high levels radiation
the quad screen is combined with what factors
mothers age and ethnicity
high AFP suggests what
spina bifida or elevated ARP levels from inaccurate dating of pregnancy
low levels AFP
abnormal hCG and estriol suggest what
baby has Trisomy 21 and 18
what causes the decrease in fetal heart rate as it develops
response to parasympathetics