Abnormal uterine bleeding and contraception Flashcards

1
Q

what can cause abnormal uterine bleeding in nongravid reproductive age women

A

Polyp
Adenomyosis
Leiomyoma
Malignancy and hyperplasia

Coagulopathy
Ovulatory Dysfunction
Endometrial
Iatrogenic
Not yet classified
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2
Q

what is an endometrial polyp

A

hyperplastic overgrowth of glands and stoma

benign

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3
Q

what can endometrial polyp cuase

A

early uterine bleeding

malignancy highger in post menopausal women

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4
Q

most common benign tumor in women

A

leiomyomas “fibroids”

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5
Q

Sx leiomyoma

A

abnormal painful menses

abdominal pain

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6
Q

what are subtypes leiomyomas

A

pedunculated
subserosal
submucosal
intramural

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7
Q

what is triad of adenomyosis

A

nocyclical pain, menorrhagia, enlarged uterus w/o adenexal tenderness

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8
Q

Tx adenomyosis

A

NSAIDs, OCPs, progestins, ablation, hysterectomy

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9
Q

fibroids are sensitive to what hormones

A

E and P

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10
Q

complications of fibroids

A

torsions and infertility

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11
Q

what is adenomyosis

A

endometrial tissue growth in myometrium

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12
Q

risk factors fibroids

A
african american
early menarche
obesity
diet, alcohol, red meats beer
HTN
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13
Q

what type of surgeries can you do for fibroids

A

myomectomy, endometrial ablation, uterine artery embolization, hysterectomy

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14
Q

types of degeneration of leiomyoma

A

hyaline
cystic
red carneous
myxoid

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15
Q

common causes postmenopausal women

A
atrophic endometrium
endometrial polyps
endometrial CA
endometrial hyperplasia
hormonal effects
cervical CA <1%
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16
Q

what causes atrophic endometrium

A

hypoE

dry vaginal epithelium that is smooth and shiny with loss of most rugation

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17
Q

why is endometrial hyperplasia weird in postmenopausal women warranting biopsy

A

because should not have hyperplasia since lack of E

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18
Q

what are classifications of endometrial hyperplasia

A

simple or complex hyperplasia without atypia

simple or complex hyperplasia with atypia

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19
Q

most common genital cancer in women over 45

A

adenoCA of endometrium

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20
Q

Tx atrophy of vagina

A

vaginal estrogen therapy

21
Q

Tx endometrial polyp

A

polypectomy

22
Q

Tx endometrial hyperplasia

A

cyclic progestin therapy

23
Q

Tx endometrial hyperplasia with atypia

A

hysterectomy

24
Q

Tx CA of endometrium

A

TAH BSO and LND for staging

25
how to Tx menorrhagia
``` ibuprofen transamic acid (expensive) ```
26
how does the implantable rod of contraception work
thickens uterus making in implantable | progesterone only
27
problems with etonogestrel implant
increase bleeding and spotting | irregularity and unpredictability
28
side effects etonogestrel implant
weight gain
29
CI etonogestrel implant
SLE with anti phospholipid Ab hepatocellular adenoma discontinue if have migraines with aura unexplained vaginal bleeding before evaluation
30
What is paragard
copper IUD no hormones--- can have heavier bleeding lasts 10 years
31
what is mirena
levonorgestrel IUD local progestin lasts 5 years
32
what disease not use copper IUD
wilsons disease
33
how does copper IUD work
alters uterine and tubal fluid hinders spermatozoa function inhibits fertilization! not abortifacient
34
how does mirena work
impaires spermatozoa motility/function | inhibits conception
35
which IUD has no weight gain
mirena
36
contraindications to IUD
current PID or within past 3 mo current cervicitis high risk women: screen first for STIs
37
what is depot provera
progesterone shot every 3 mo | thickens cervical mucus
38
side effects depot provera
bleeding irregularities weight gain delayed return fertility decrease in bone mineral density
39
how does depot provera change BMD
loss of BMD | returns to baseline once discontinued
40
few CI to depot provera
severe HTN | DM with vascular disease
41
special populations to use depot provera
sickle cell | epileptics
42
which contraceptive use is weight dependent
the patch | >90 kg doesn't work
43
what is in nuva ring
ethinyl estradiol | etonorgestrel
44
when is back up method for nuva ring needed
taken out for greater than 3 hours
45
what increases weight
depot provera
46
breakthrough bleeding more common in
smokers | cervical infections
47
CI to oral contraception
``` Hx VTE known thrombogenic mutation migraines WITH aura HTN poorly controlled lupus with antiphospholipid Ab (hypercoaguable) ```
48
method for protection from STIs
condoms