PROM and chorioamnionitis and postpartum hemorrhage Flashcards

1
Q

risks for preterm premature rupture of uterine membranes

A

previous PROM, preterm labor, vaginal uteral infections, smoking, mechanical stress, GU tract infections, antepartum bleeding

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2
Q

tests to see if membranes have ruptured

A

nitrazine and fern test(amnionitc fluid detection)

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3
Q

need to rule out what for pprom

A

urinary incontinence, vaginal discharge, perspiration

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4
Q

when is PPROM

A

PROM before 37 weeks gestation

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5
Q

what is mid trimester PROM

A

PROM 14-26 weeks gestation

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6
Q

women with PPROM have increased risk of what

A

placental abruption
umbilical cord prolapse
pulmonary hypoplasia

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7
Q

Tx PPROM

A

delivery asap

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8
Q

when do we give antibiotics for those with PPROM

A

24-32 weeks

>32 weeks but <34 weeks

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9
Q

what antibiotic is used in PPROM? for what pathogen?

A

ampicillin IV

group B strep

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10
Q

what steroid is given to mom if PPROM

A

bethamethasone for lung maturity

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11
Q

what are tocolytics

A

delay delivery for 48 hours

Mg sulfate

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12
Q

side effects Mg sulfate

A

HA flushing, fatigue, diplopia, DTRs

respiratory depression and cardiac arrest at toxic levels

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13
Q

what antibiotic is given for chlamydia tachomatis

A

azithromycin

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14
Q

if penicillin allergy in mom with PPROM what is given

A

clinda or genta. or cefazolin and cephalexin

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15
Q

mother with difficult labor
temperature rises and foul odor present
tachycardia
Dx? and Tx?

A

chorioamnionitis

gentamycin, clinda or vanco

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16
Q

what is chorioamnionitis

A

infection of amniotic fluid, membranes, placenta or decidua

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17
Q

chorioamnionitis is associated with what complications

A

early neonatal sepsis and penumonia

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18
Q

what is a common cause of transplacental infection

A

listeria monocytogenes

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19
Q

what procedures could increase risk of chorioamnionitis

A

amniocentesis, chorionic villus sampling, fetal surgery

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20
Q

risk factors for chorioamnionitis

A
prolonged labor, prolonged membrane rupture
multiple digital vaginal examinations
nulliparity
previous IAI
meconium stained amniotic fluid,
internal fetal or uterine monitoring
presence of genital tract pathogens
alcohol
tobacco
PROM
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21
Q

clinical presentation of chorioamnionitis

A
fever
uterine tenderness
maternal tachy
fetal tachy
purulent or foul amniotic fluid
maternal leukocytosis
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22
Q

risks with labor if have chorioamnionitis

A

uterine atony
postpartum hemorrhage
endometritis

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23
Q

how can chorioamnionitis affect contractions

A

dysfunctional myometrial contractility from inflammation

24
Q

risks if C section with chorioamnionitis

A

wound infection, endomyometritis

venous thrombosis

25
what is ddx for chorioamnionitis
pyelonephritis, influenza, appendicitis, pneumonia
26
most specific documentation for intraamnionic infection
culture of amniotic fluid
27
standard Tx for chorioamnionitis
ampicillin 2 g IV q 6 hours | gentamycin 1.5mg/kg q8hr
28
what to use for Tx in chorioamnionitis when patient has penicillin allergy
vanco
29
causes of uterine rupture related to pregnancy
chorioamnionitis abruptio placentae rupture of gravid uterus
30
causes of uterine rupture uncrelated to pregnancy
torsion ovarian cyst or rupture strangulated hernia, intestinal obstruction renal colic, acute appendicitis
31
anatomical sites of uterine rupture
anterior left transverse, lateral, fundal, combination
32
associations of prio births with uterine rupture
previous c section previous uterine surgery cervical cerclage in place
33
risk factors uterine rupture
``` previous uterine surgery use of uterotonic drugs instrument assisted delivery prolonged and obstructed labor early pregnancy in young immature girls malnutrition tradition (female circumcision) ```
34
initial care of uterine rupture
resuscitation with crystalloid fluids, blood products gastric decompression urinary catheterization broad spectrum antibiotics
35
what laparotomy techniques are used for uterine rupture
repaire w/ or w/o tubal ligation | TAH
36
post op for uterine rupture
transfusion, bladder rest, wound care, antibiotics counseling monitor for obstetrical fistula
37
significant bleeding in 31 wk pregnant woman some contractions, no abdominal pain, no recent trauma, mass in abdomen mobile nontender ddx?
``` placenta previa placenta abruption displacement cervical mucus plug PROM cervicitis vaginitis/vulvovaginitis ```
38
painless bleeding in third trimester, imaging?
transvaginal US
39
hemabate is used for what
stop bleeding
40
what is placenta previa
placental tissue over or adjacent to os
41
what is marginal placenta previa
edge of placenta is at margin of internal os
42
what is low lying placenta
placenta is implanted in lower uterin segment and does not reach os but is close
43
what is vasa previa
fetal vessels present at cervical os
44
risk factors placenta previa
``` previous one previous c section multiple gestation multiparity advanced maternal age infertility Tx previous abortion previous intrauterine surgical procedure maternal smoking maternal cocaine use male fetus non-white race ```
45
tx asymptomatic previa
monitor with US as outpatient, avoid strenuous exercise, planned CS for delivery
46
Tx bleeding previa
potential EM | hospitalize for monitoring, CS if hemorrhage
47
when is vaginal delivery attempted in placenta previa
if placental edge is > 10 mm from internal os due to lower risk of hemorrhage during labor
48
what is too much blood loss in vaginal delivery? CS?
>500mL vaginal | >1000 mL CS
49
what are the 4 Ts of postpartum hemorrhage
tone trauma tissue thrombus
50
what is tone in postpartum hemorrhage
no contraciton, sprial arterioles and decidual vv continue to bleed
51
Tx of atony in postpartum hemorrhage
massage pitocin and cytotec methergine or hemabate
52
methergine should not be used to stop bleeding in what patients
HTN
53
hemabate should not be used to stop bleeding in what patients
asthma
54
causes of PPH from trauma
``` lacerations (forceps or extractors) uterine inversion (improper management in 3rd stage of labor) ```
55
Tx if uterus is unable to contract and involute around retained placental tissue mass
manual removal | dilation and curettage
56
what type of thombi can cause postpartum hemorrhage
ITP platelets) amnionic fluid embolus vwDisease
57
Tx for thrombi causing post partum hemorrhage
coagulation studies