male Path II

Question 1

common spot for condyloma accuminata in men

Answer 1

coronal sulcus and inner surface prepuce

Question 2

what is a sign of bowden disase

Answer 2

red or grey plaque on shaft

carcinoma in situ

Question 3

what is erythroplasia of querat

Answer 3

shiny soft red plaque on glans and foreskin

Question 4

all carcinomas in situ of penis have what in common

Answer 4

clinical variants of HPV 16

Question 5

what are bowenoid papulosis

Answer 5

red tan papules in young adults. DOES NOT progress to invasive SCC

Question 6

HPV E6 and e7

Answer 6

E6 inactivates p53

E7 inactivates pRB

Question 7

koilocyte

Answer 7

high risk HPV

Question 8

CIS of penis

Answer 8

bowens disease

erythroplasia of querat

Question 9

risk factors SCC penis

Answer 9

lack of circumscision
assoc HPV 16 18
occurs between 40&70
association with smoking

Question 10

prognosis SCC penis depends on

Answer 10

spread to regional lymph nodes

Question 11

how do invasive SCC penis present

Answer 11

painless slow growing tumors

Question 12

tumor Bx from penis show islands of keratin and “pearls”

Answer 12

invasive SCC

Question 13

what are pearly penile papules

Answer 13

not HPV or genital wart
white papules in rows
disapears after years

Question 14

dusky blue appearance over testicle in young boy complaining of pain

Answer 14

torsion of appendix testis

Question 15

what is tunica albuginea

Answer 15

covers testis

Question 16

where do hydroceles form

Answer 16

in scrotal cavity

Question 17

what is it called if infection in scrotal cavity

Answer 17

pyocele

Question 18

cryptorchidism

Answer 18

failure of testicle to descend into scrotum

Question 19

phases of testicular descent

Answer 19

transabdominal (sertoli cells make AMH andwolffiant duct develops when T present)
inguinal-scrotal phase: craniosuspensory ligament dissolves and gubernaculum guides testis to scotum

Question 20

what hormones are needed for testicular descent

Answer 20

1: AMH and T
2: androgens

Question 21

cryptorchidism is assoc with

Answer 21

klinefelter, premature birth and +FMH

Question 22

cryptorchidism patients are at higher risk for

Answer 22

testicular CA, trauma, torsion and infertility

Question 23

Tx cryptorchidsm

Answer 23

surgical correction

orchiopexy

Question 24

where are sertoli and leydig cells found

Answer 24

sertoli in the germ cell area

leydig in stroma

Question 25

majority testicles that do not descend are located where

Answer 25

high scrotum>inguinal canal>abdomen

Question 26

conditions assoc with b/l atrophy of testicles

Answer 26

chronic alcoholism, hypopituitarism, atherosclerosis, chemo, radiation, severe prolonged illness

Question 27

on microscopy of testicle see leydig cell hyperplasia, peritubular fibrosis and only sertoli cells in the tubles

Answer 27

cryptorchid

Question 28

what is eagle barrett syndrome

Answer 28

prune belly syndrome have b/l cryptorchidism absence abdominal muscles

Question 29

in infant see severely swollen scrotum

Answer 29

torsion

Question 30

which direction does testicular torsion usually occur

Answer 30

medially

Question 31

how long do you have to recognize testicular torsion

Answer 31

12 hours

Question 32

bell claper deformity

Answer 32

when testicle is in horizontal position

Question 33

Dx torsion

Answer 33

doppler

Question 34

what bacteria cause epididymitis in young men

Answer 34

gonorrhea, chlamydia

Question 35

what bacteria cause epididymitis in old men

Answer 35

E coli from UTI

Question 36

what infections affect testicle before epididymis

Answer 36

syphilis mumps gram - bacteria

Question 37

best way to Dx infeciton of testicle or epididymis

Answer 37

culture UA

Question 38

what can cause granulomatous orchitis

Answer 38

post vasectomy because seminal fluid gets around an into cavity

Question 39

many PMNs in epididymal ducts

Answer 39

infection

Question 40

what are the germ cell tumors

Answer 40

seminomatous | non seminomatous

Question 41

what are the sex cord stromal tumors

Answer 41

leydig cell tumor and sertoli cell tumor

Question 42

what lymphoma occurs in testicles

Answer 42

non hodgkin diffuse B cell lymphoma