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Year2 Repro exam II > male Path II > Flashcards

male Path II Flashcards

1
Q

common spot for condyloma accuminata in men

A

coronal sulcus and inner surface prepuce

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2
Q

what is a sign of bowden disase

A

red or grey plaque on shaft

carcinoma in situ

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3
Q

what is erythroplasia of querat

A

shiny soft red plaque on glans and foreskin

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4
Q

all carcinomas in situ of penis have what in common

A

clinical variants of HPV 16

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5
Q

what are bowenoid papulosis

A

red tan papules in young adults. DOES NOT progress to invasive SCC

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6
Q

HPV E6 and e7

A

E6 inactivates p53

E7 inactivates pRB

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7
Q

koilocyte

A

high risk HPV

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8
Q

CIS of penis

A

bowens disease

erythroplasia of querat

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9
Q

risk factors SCC penis

A

lack of circumscision
assoc HPV 16 18
occurs between 40&70
association with smoking

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10
Q

prognosis SCC penis depends on

A

spread to regional lymph nodes

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11
Q

how do invasive SCC penis present

A

painless slow growing tumors

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12
Q

tumor Bx from penis show islands of keratin and “pearls”

A

invasive SCC

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13
Q

what are pearly penile papules

A

not HPV or genital wart
white papules in rows
disapears after years

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14
Q

dusky blue appearance over testicle in young boy complaining of pain

A

torsion of appendix testis

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15
Q

what is tunica albuginea

A

covers testis

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16
Q

where do hydroceles form

A

in scrotal cavity

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17
Q

what is it called if infection in scrotal cavity

A

pyocele

18
Q

cryptorchidism

A

failure of testicle to descend into scrotum

19
Q

phases of testicular descent

A

transabdominal (sertoli cells make AMH andwolffiant duct develops when T present)
inguinal-scrotal phase: craniosuspensory ligament dissolves and gubernaculum guides testis to scotum

20
Q

what hormones are needed for testicular descent

A

1: AMH and T
2: androgens

21
Q

cryptorchidism is assoc with

A

klinefelter, premature birth and +FMH

22
Q

cryptorchidism patients are at higher risk for

A

testicular CA, trauma, torsion and infertility

23
Q

Tx cryptorchidsm

A

surgical correction

orchiopexy

24
Q

where are sertoli and leydig cells found

A

sertoli in the germ cell area

leydig in stroma

25
Q

majority testicles that do not descend are located where

A

high scrotum>inguinal canal>abdomen

26
Q

conditions assoc with b/l atrophy of testicles

A

chronic alcoholism, hypopituitarism, atherosclerosis, chemo, radiation, severe prolonged illness

27
Q

on microscopy of testicle see leydig cell hyperplasia, peritubular fibrosis and only sertoli cells in the tubles

A

cryptorchid

28
Q

what is eagle barrett syndrome

A

prune belly syndrome
have b/l cryptorchidism
absence abdominal muscles

29
Q

in infant see severely swollen scrotum

A

torsion

30
Q

which direction does testicular torsion usually occur

A

medially

31
Q

how long do you have to recognize testicular torsion

A

12 hours

32
Q

bell claper deformity

A

when testicle is in horizontal position

33
Q

Dx torsion

A

doppler

34
Q

what bacteria cause epididymitis in young men

A

gonorrhea, chlamydia

35
Q

what bacteria cause epididymitis in old men

A

E coli from UTI

36
Q

what infections affect testicle before epididymis

A

syphilis
mumps
gram - bacteria

37
Q

best way to Dx infeciton of testicle or epididymis

A

culture UA

38
Q

what can cause granulomatous orchitis

A

post vasectomy because seminal fluid gets around an into cavity

39
Q

many PMNs in epididymal ducts

A

infection

40
Q

what are the germ cell tumors

A

seminomatous

non seminomatous

41
Q

what are the sex cord stromal tumors

A

leydig cell tumor and sertoli cell tumor

42
Q

what lymphoma occurs in testicles

A

non hodgkin diffuse B cell lymphoma

Year2 Repro exam II (19 decks)

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